These facts are satisfactory thus far, and it would be abundantly easy to add to them; but there is reason to suspect that it can be conveyed to far greater distances, in certain favourable circumstances: those reasons, in the first place, being derived from certain meteorological analogies and considerations, and in the next confirmed by experience. It is notorious that the ague appears on our eastern coasts with the first east winds of spring; and while this circumstance is most common on those of England, as for example, in Kent, Essex, Norfolk, [p046] Suffolk, and Lincolnshire, it is not thus limited, since it is known to happen further north, and even in Scotland, where malaria is not indigenous to the soil. It is very true that if we take any inland position in the places thus noted, the natural solution is, that the malaria is generated in the very soil itself of England, and merely propagated, perhaps even to very moderate distances, through those winds. But the occurrence of disease cannot be explained thus, when the place in question is so situated that there is no land to the eastward, or when the breeze is, most literally and rigidly, a sea breeze; while, when ague thus occurs on the east coast of Scotland, where it is not produced by the soil, it must be imported by the east wind. These are the facts; while as malaria is not produced by the sea itself in any known circumstance, though a vegetating sea beach may give rise to it, we must seek the cause in lands far distant, and consider this as a case of propagation of the poison from the shores of Holland; and those shores are unquestionably competent to that effect: so that the only question that remains, the fact being admitted, is, whether, _à priori_, or theoretically, such a view is probable, or whether it is consistent with those physical principles that are concerned in the propagation of malaria.