"I have been thus explicit in this description, from the fact that recent investigation has developed the fact that in the discovery described above, I had found but a prototype of at least seven-tenths of the human family in civilized life--the real cause of all diseases of the human body, excepting the grape seed and popcorn. That I had found the fountain of premature old age and death, for, as surprising as it may seem, out of 284 cases of autopsies held of late on the colon (they representing in their death nearly all the diseases known to our climate), but twenty-eight colons were found to be free from hardened, adhered matter, and in their normal healthy state, and that the 256 were all more or less as described above, except, perhaps, the grape seeds and popcorn. In many of them the colon was distended to double its natural size throughout its whole length, with a small hole through the center, and as far as could be learned, these last cases spoken of had regular evacuations of the bowels each day. Many of the colons contained large maggots from four to six inches long, and pockets of eggs and maggots, while blood and pus were frequently present." The question is often asked, and naturally so, why this unnatural accumulation is in the colon? The horse and ox promptly obey the call of nature; they know no time or place, and are blessed with clean colons. So are the natives of Africa. But the demands of civilized life insist upon a time and place. Business, etiquette, opportunity, and a thousand and one excuses stand continually in the way, and nature's call is put off to a more convenient time and place.