It is indeed high time, that by means of discoveries which will enable us to predict with certainty the nature of coming seasons, we shall be better enabled to cope with adversities in agriculture; also, that the numerous wrecks, and the thousands of lives lost with them every year on our coasts, should be diminished. But these desirable results cannot be effected by invention based upon insufficient knowledge; invention must be preceded by general as well as special research, because the former often discloses important {78} truths which we cannot predict. Our present electric lights in light-houses and on large ocean steamers, had their origin, not in direct inventions or special researches for the purpose, but in abstract researches on apparently remote subjects. It is nothing less than a national crime that proper provision has not yet been made for investigating scientifically the causes of famine and pestilence, also physiology and pathology, and the discovery of the laws which regulate diseases and epidemics. What can be more painful to behold than a mother and father deprived of a whole family of five or six children in rapid succession by scarlatina or other contagious disease, and both the parents and medical men utterly unable to save them; and this is a common occurrence. Persons who are ignorant of science look with an abject feeling of helplessness upon great national calamities, and even upon private afflictions, such as a local epidemic, as if there was absolutely no remedy, whilst scientific men believe that by extension of knowledge, such evils might be largely avoided or prevented. Many persons however, actuated by the very kindest of motives, but insufficiently acquainted with the necessity, conditions, results, and advantages of experiments, unwittingly obstruct the discovery of new knowledge in physiology and pathology, by attempting to prevent experiments being made upon animals.