one of Serapion’s authorities, thus sums up its characters: it is hot and dry in the end of the second degree; cuts and dissolves viscid and congealed phlegm, and therefore opens all the pores and passages which are shut up; provokes urine and the menstrua; and is beneficial in asthma and all cold pituitous ailments. The seeds of seseli held a place in our Dispensatory as late as the times of Quincy (158), and of Lewis (ii, 366.) Σηπία, Sepia, _the Cuttlefish_; its shell has powers like those of an oyster, but is attenuant and more detergent; hence, if burnt, it attenuates pterygium along with fossil salts. When unburnt it clears away sycosis when rubbed upon the part, and proves detergent to the skin. * * * * * COMMENTARY. It is the _Sepia Loligo_, L. We need scarcely mention that the shells of fishes consist principally of lime. As represented by the ancients, therefore, they form a detergent application to the skin. All the authorities recommend it in nearly the same cases, namely, as an ingredient in stimulant collyria, and in obstinate cutaneous diseases, and as a dentifrice. See Dioscorides (ii, 23); Galen (De Simpl.); Celsus (v, 29); Aëtius (ii, 190.) Aëtius gives the fullest account of this article. (l. c.) Σησαμοειδὲς, Sesamoides; the seed of the white species heats, is detergent, and procures the rupture of abscesses. * * * * * COMMENTARY. This article, which occurs in the Hippocratic treatises, and of which two species, the great and the small, are described by Dioscorides, has been the subject of much controversy. See Parkinson, Sprengel, and Dierbach. We are willing to acquiesce in Sprengel’s decision regarding them, namely, that they are the _Reseda Mediterranea_ and _canescens_. It appears that they were used principally in combination with hellebore, and that the one evacuated upwards, and the other downwards. (Dioscor. iv, 150, 151.) Ruffus treats only of the small, which he represents to be cholagogue and phlegmagogue, when its seed is taken to the amount of an acetabulum. (De Med. Purg.) It does not occur in the works of Celsus, and does not seem to have been much in repute. Galen gives nearly the same account of it as Dioscorides. We have not found it in the works of the Arabians, with the exception of Ebn Baithar, one of whose Arabian authorities speaks of its being used in paralysis. (i, 252.) Σήσαμον, Sesamum, _Oily-grain_, is glutinous and fatty in no small degree; hence it is emplastic, emollient, and moderately calefacient. * * * * *