No permanent settlement was then made, but the reports of thousands of peaceable and wealthy Indians inhabiting irrigated valleys, and the accounts of the magnificent pastures which stretched away to the east, soon tempted the Spaniards to take permanent possession. Seven years after the first exploration a town was founded in latitude 27 deg., midway between the Andes and the Parana. About the same time other adventurers came pouring over the Andes from northern Chile, and this current soon joined that from the north. The Spaniards established themselves as feudal lords, and the unhappy Indians were divided among them. In one district, forty-seven thousand Indians were divided among fifty-six grantees. In 1553, Santiago de Estero, for many years the capital of the province of Tucuman was founded. In 1561, the governor of Chile sent from Santiago de Chile over the Andes an expedition which founded the city of Mendoza in a most beautiful region, where the vine flourishes in perfection, and where a wonderful system of irrigation, inherited from the Indians, still exists to attest the latters' engineering skill. Next year San Juan was founded, and these two towns were the centres for the settlement of the province of Cuyo, which remained a part of Chile for two hundred years. The immigrants from northern Chile and Bolivia established Tucuman in the tropical garden spot of the republic in 1565. From Santiago del Estero, in 1573, an expedition was sent two hundred and fifty miles to the south to a region of fertile valleys and plains at the foot of a beautiful mountain range. This was Cordoba, which at once became, and has since remained, the most populous of the interior provinces. By the end of the sixteenth century the Spanish power was firmly established in settlements that have since become the Argentine provinces of Jujuy, Salta, Tucuman, Catamarca, Santiago, Rioja, and Cordoba. All these really formed a southern extension of Upper Peru. Their geographical, political, and commercial relations were with Charcas, Potosi, and Lima. The discovery, in 1545, of the great silver mines at Potosi at once made the high Bolivian plateau, then known as the Audiencia of Charcas, the most valuable and important province of all the Spanish monarch's South American empire. In 1571, the discovery of quicksilver mines in Peru vastly increased the output of precious metals; in 1575, the wonderful Oruro mines were opened, and before the end of the century the copper-pan amalgamation process was invented in Bolivia, revolutionising the production of silver. [Illustration: MINING SCENE. [Redrawn from Gottfriedt's _Neuw Welt_.]]