Jenner was unable to comply with Cline’s request: he had no cowpox to transmit: and readers of the _Inquiry_ who addressed to him similar requests had to submit to similar disappointments, out of which some suspicion was naturally developed. The recommendation of a remedy whereof there was no available supply was not a passport to confidence. Baron relates, that “Mr. Cline perceiving _at once_ from the success of his first trial, what incalculable blessings were connected with the diffusion of the new practice, immediately advised Jenner to quit the country, and to take a house in Grosvenor Square, and promised him £10,000 per annum as the result of his practice; in which opinion Mr. Cline was supported by Sir W. Farquhar; but that all these splendid prospects of wealth and distinction could not move Jenner.”[101] The story is either an invention, or it does little credit to Cline’s judgment. Jenner had neither the means for a house in Grosvenor Square, nor was there any likelihood of his earning £10,000 a year by cowpox. Nevertheless it would appear that at this juncture some one was advising him to try London (one’s vanity is never without a prompter), and that Jenner replied-- CHELTENHAM, _29th September_. My perplexity really amounts to agitation. On the one hand, unwilling to come to town myself for the sake of practice, and, on the other, fearful that the practice I have recommended may fall into the hands of those who are incapable of conducting it, I am thrown into a state that was not at first perceptible as likely to happen to me; for, believe me, I am not callous to all the feelings of those wounds which, from misrepresentation, might fall on my reputation; on the contrary, no nerves could feel more acutely; and they now are actually in a tremor from anticipation. How very few are capable of conducting physiological experiments! I am fearful that before we thoroughly understand what is cowpox matter, and what is not, some confusion may arise, for which I shall, unjustly, be made answerable.[102] If his correspondent had been a man of sense, he might have replied-- Why so much ado about nothing! You recommend that horsegrease cowpox be substituted for smallpox in cases of inoculation. It is a simple prescription, easily determined altogether apart from you, and there is no reason why you should work yourself into such a flutter.