The youthful king had none to help him. His father Dom João, the only son of John III., had died fifteen days before the birth of his only child, and his mother, Donna Joanna, the daughter of the Emperor Charles V., had immediately retired to Spain, leaving the child to the care of his grandparents. On the death of John III. in 1557, his queen, Donna Catherine, the sister of Charles V., assumed the regency in the name of her grandson. From the very first, the Portuguese people, from the highest to the lowest, disapproved of her rule; she was so aggressively Spanish in speech, bearing, and appearance, and had so persistently refused to identify herself with her adopted country, in spite of her long residence there, that every one believed her to be plotting to secure the eventual succession of her favourite nephew, Philip II. of Spain, to the crown of Portugal. Her bigotry and encouragement of the Inquisition did not tend to make her popular, and national prejudice declared itself strongly against her. Yet she was not a bad ruler; she maintained the old servants of John III., and the machinery of administration though in many places clogged by corruption, went on smoothly, and she even managed to despatch a sufficiently powerful army to relieve Mazagon, when it was besieged by the Moors. Yet throughout her five years’ tenure of power the queen-regent found herself hampered by the intrigues of the Cardinal Henry, who, as heir to the throne, thought he ought to be in her place, and at last she decided to give up the struggle, and in 1562 she retired to Spain. The Cardinal Henry then satisfied his ambition and became regent of the kingdom, of which he was to be for a short time the unfortunate monarch, and during his rule the government of the country fell entirely into the hands of two brothers, who had made themselves very conspicuous in the intrigues which had led to the retirement of Queen Catherine. Of these brothers, the elder, Luis Gonçalves da Camara, was an able Jesuit, who had been appointed confessor and tutor to the young king, while the younger, Martim, was prime minister, and carried on the work of administration during the regency of the Cardinal Henry. The two brothers were both men of considerable ability, and, though they made no attempt to initiate reforms or to check the decay of Portugal, they managed to conceal her rottenness as much as possible from the eyes of Europe. In 1568 Dom Sebastian was declared of age by the Camaras, though only in his fifteenth year, and from that time they excluded their former master, the Cardinal, from even a semblance of power. This behaviour did not ensure their continuance in office, for as soon as the young king began to take an active interest in affairs, he dismissed the brothers, and placed the chief power in the hands of an upright nobleman, Dom Pedro de Alçaçova Carneiro.