The suppression of tuberculosis: $b Together with observations concerning phthisiogenesis in man and animals and suggestions concerning the hygiene of cow stables and the production of milk for infant-feeding, with special reference to tuberculosisBehring, Emil von
Science
The suppression of tuberculosis: $b Together with observations concerning phthisiogenesis in man and animals and suggestions concerning the hygiene of cow stables and the production of milk for infant-feeding, with special reference to tuberculosis
Behring, Emil von
Tuberculosis -- Prevention
31. The acute miliary tuberculosis in man, which can be clinically
diagnosticated, is to be regarded as a provocative secondary infection,
resulting from scrofula of the blood-vessels’ intima when, on the
disintegration of cheesy intima tubercles, a great many tubercle
bacilli are thrown into the circulation at once. (Weigert-Ponfick.)
32. Disease of the lung apices occurring in the virile period of
infection and, because of its important bearing on the origin of
consumption, considered separately, is preceded by the consequences
of an infantile infection. Foremost among these is the secondary
hypoplasia of the smooth muscle tissue (of vessels, bronchi, and
intestinal wall); next in order come wasting [Veröding] of the
lymphatic apparatus (quantitative and qualitative reduction of
the follicular receptive apparatus of the _tubus alimentarius_);
destruction of lymph-glands; and the secondary hypoplasia of other
primary points of attack for Tb. action (in the spleen, bone-marrow
cavities, on serous surfaces of the large body cavities, and of the
joints). The predilection of the thoracic dome for immobilizing
changes can probably be ascribed to its exposure to the Tb. infection
in connection with precedent mediastinal-gland scrofula; while the
predilection of the lung apices for caseating lesions can again be
brought into causal relation with secondary ossifying processes, of
scrofulous origin, in the joint structures of the thoracic dome (cf.
Aufrecht, 1. c.).
33. In my experiments on tubercular cattle I succeeded in producing
eruptions of gray, non-caseating tubercles, running an acute course, by
means of injections of tuberculin. At the same time it was noticed that
not infrequently after the intercurrent exacerbation had subsided, the
old infectious process had been favorably influenced.
34. Even when caseating lesions are present, the simultaneously
developing submiliary transparent eruptions (granulie, of the older
authors) are to be regarded as capable of being organized and
spontaneously cured. They are much more numerous in man than has
heretofore been assumed. This is shown, for example, by the fact that
upon opening the abdominal cavity of such young individuals as showed
no clinically diagnosticated symptoms of a miliary tuberculosis, these
eruptions were by chance demonstrated.
It is of the highest interest to determine the fate of such individuals
with a healed miliary tuberculosis of the peritoneum, that is,
whether in virile period of life the disposition in them to pulmonary
consumption is increased or diminished.
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