Through the courtesy of Count Zedlitz I was enabled to make numerous preventative inoculations on cattle in three counties of Hesse-Nassau; from there the experiments were extended to the neighboring grand duchy of Hesse, and to the large dairy of Bolle in Köpenik near Berlin. As a result of this work I was able in the beginning of this year to establish the harmlessness of the procedure. Since then I have had abundant opportunity to inoculate calves under three months on the immense Hungarian possessions of Prince Ludwig of Bavaria; also on those of Archduke Frederick of Austria. Under my direction scientific researches regarding the protection afforded by the inoculations have been undertaken by Prof. Eber in the veterinary school of the University of Leipzig and by Prof. Schlegel in that of the University of Freiburg; further also by Ober-med. Rath Lorenz in Darmstadt and by Prof. Hutyra in Budapest. In Marburg I myself have made studies on highly immunized cattle regarding the production of anti-bodies, have reared calves on cows immune to tuberculosis, and have investigated the subject of immune milk. All the details have been carefully recorded. Some of these protocols have already been printed, and at the close of this year I hope to commence the publication and working out of the rest of this enormous mass of material in my “_Beiträge zur experimentellen Therapie_.” In the mean time, however, the practical application of my immunizing procedure continues steadily to gain in extent. Austrian as well as Swedish investigators, sent by their governments to study the inoculation technique at Marburg, are to make extensive inoculations in their native countries. The government of the grand duchy of Hesse has ordered that the counties use part of their police fund to defray the expense of inoculating all calves free of charge, provided that the owners bind themselves to allow the county veterinarian to supervise the inoculated animals. From all sides I receive requests for this preventative virus. Until recently I prepared this virus myself and distributed it free of charge with the help of private funds. I was able to do the entire scientific, technical, and administrative work with only a few assistants. But this is no longer possible, for the expenses have outgrown not only my financial means, but also, even with great zeal for the work, my bodily strength. I should gladly have postponed any change in the manufacture and distribution of the virus until the Prussian government was ready to take charge of the entire matter. But the daily increasing labor has made it necessary for me to rid myself of this burden now, and I have therefore provisionally arranged that the firm of Drs. Seibert & Ziegenbein of Marburg undertake the manufacture.