-------------+------+------------------------------------------------- |Effect| Dose per kilo (grams) Animal. |of +---------+-----------+-----------+-------+------- |dose. | SC | BM | IP | IM | IV -------------+------+---------+-----------+-----------+-------+------- Rabbit, gray |{Toxic| 0.15| 0.325| 0.100| 0.13| 0.05 | | | | -0.125 | -0.15| |{Fatal| .30| .350| .150| .20| 0.10 | | | | | | -.16 Rabbit, white|{Toxic| | | | | or black |{Fatal| .20| .290| | | | | | | | | Guinea pig |{Toxic|0.15- .16| .150| .200| | |{Fatal| .20- .24|0.280- .300| .240- .250| | | | | | | | Cat |{Toxic| .12- .14| .125| .125- .150| | |{Fatal| .15| .150| .180- .200| | | | | | | | Dog |{Toxic| | .100- .120| | | |{Fatal| .15- .16| .140- .150| | | -------------+------+---------+-----------+-----------+-------+------- NOTE.--The doses given in this table are approximate. CAFFEIN BIBLIOGRAPHY. 1. ABDERHALDEN and BRAHM. Zts. Physiol. Chem., 1909, =62=: 133. 2. ALBERS. Deut. Klin., 1852, =5=: 577. 3. AMAT. Diss. Paris, 1889. 4. AMORY. Boston Med. Surg. J., 1868, =1=: 261. 5. VON ANREP. Arch. Ges. Phys., 1880, =21=: 185. 6. AUBERT. Pflüger's Arch., 1872, =5=: 589. 7. AUER and MELTZER. J. Pharm. Exper. Ther., 1911, =2=: 402. 8. BALDI. Terapia Moderna, 1891, =5=: 617. 9. BENNETT. Brit. Med. J., 1874, =2=: 674. 10. BERNARD, CLAUDE. Leçons sur les substances toxiques, Paris, 1857, p. 292. 11. BINZ. Arch. Exper. Path. Pharm., 1878, =9=: 31. 12. ---- Ibid., 1891, =28=: 197. 13. BRILL. Diss. Marburg, 1861. 14. BUCHHEIM and EISENMENGER. Beitr. Anat. Physiol., 1870, =5=: 115. 15. BUNGE and SCHMIEDEBERG. Arch. Exper. Path. Pharm., 1876, =6=: 233. 16. CHITTENDEN. The Nutrition of Man, 1907. 17. COGSWELL. Lancet (London), 1852, =2=: 488. 18. DANILEWSKI. Arch. Exper. Path. Pharm., 1894, =35=: 105. 19. DRZEWINA. Compt. rend. Soc. biol., 1911, =70=: 772. 20. DUMAS and PELLETIER. Ann. chim. phys., 1823, =24=: 182. 21. EDMUNDS. J. Amer. Med. Assoc., 1907, =48=: 1744. 22. FILEHNE. Arch. Phys., 1886, p. 72. 23. FLEISCHER and LOEB. Archives of Internal Medicine, 1909, =3=: 78. 24. FOCKE. Arch. Pharm., 1903, =241=: 678. 25. FRERICHS. Handwörterbuch Phys., 1846, =3=: 721. 26. FRÖHNER. Monats. prakt. Tierh., 1892, =3=: 529. 27. GENTILHOMME. Bull. Soc. Med. Reims, 1867, =5=: 93.