June 5: 2.20 p. m., 25 cc of 2 per cent caffein (0.15 gram per kilo) given by mouth; 2.45 p. m., cat irritable, no other symptoms (cat did not vomit after the administration of caffein); 4 p. m., cat found dead. _Autopsy_: Liver very much congested; heart contracted; body was still warm at the time of autopsy. _Cat 90. White and yellow female. Weight, 2,685 grams. Diet, meat._ June 5: 3.15 p. m., 27 cc of 2 per cent caffein (0.2 gram per kilo) given by mouth through stomach tube, about half an hour later cat became irritable and began to salivate; at 4.30 p. m. salivation became more marked, dyspnoea was well developed, and the cat was quite restless and had tremors; 5 p. m., short spasms of posterior extremities, but lay quietly in the cage most of the time; 5.20 p. m., convulsions of short duration and death, muscular relaxation followed immediately after convulsions, no vomiting, diarrhea observed after administration of caffein, and cat passed about 10 cc of urine. June 6: 9 a. m., found dead. _Cat 89. White and black female. Weight, 2,860 grams. Diet, meat._ June 5: 3.15 p. m., 28.6 cc (0.2 gram per kilo) of 2 per cent caffein given by mouth through stomach tube, no vomiting observed, nor any other symptoms; 3.30, found dead. _Autopsy_: Organs normal; liver congested. _Cat 82. Gray female. March 3, weight 2,450 grams; June 6, weight 2,750 grams. Diet, 150 grams of meat daily._ June 7: Given 0.4125 gram of caffein in 150 grams of meat, did not eat. June 8: Given 0.4125 gram of caffein in 150 grams of meat, refused to eat. June 9: Given 150 grams of meat without caffein, ate all of it. June 10: No food given. June 11: No food given. June 12: Given 0.4125 gram caffein in 150 grams of meat (150 mg per kilo), ate all of it. June 13: Found dead. _Autopsy_: Lungs congested, liver congested; other organs apparently normal. _Cat 100. Gray female. Weight, 2,740 grams. Diet, meat._ July 17: 3 p. m., 17 cc of 2 per cent caffein (124 mg per kilo) given by mouth through stomach tube at 3.20 p. m.; 5 p. m., very irritable, but no other symptoms. July 18: Under observation all day, no symptoms. _Cat 93. Black and white female. Weight, 1,640 grams._ July 17: 3.30 p. m., 10 cc (0.125 gram per kilo) of 2 per cent caffein given by mouth through stomach tube. July 18: Under observation all day, no symptoms.