Naja tripudians 0.00047
Naja hagé 0.0003-0.0007
Acanthophis antarctica 0.001
Ceraste 0.0017-0.0021
Haplocephalus variegatus 0.0025
Trigonocephalus 0.0025
[144] CALMETTE: _Annal. Instit. Pasteur_, VIII, p. 276; IX, p. 229.
=Nature of Serpent-venoms.=--These venoms are homogeneous liquids,
somewhat more dense than water, in which they are soluble, slightly
colored green or yellow, transparent, and insoluble in alcohol; they
contain from 30 to 35 per cent. of solid matter. When fresh, they have
a slightly acid reaction. Towards chemical reagents, and particularly
acids, they behave like albuminoids; almost all the combinations they
afford with the various albuminoid reagents are active, despite their
insolubility. According to Gautier, they are decomposed by caustic
potash.
According to numerous researches, oxidizers like potassium
permanganate, the hypochlorites, hydrogen peroxide, and gold chloride
(in 1% solution) destroy the venoms; in certain cases when immediately
injected hypodermically in the poisoned region, these substances are
excellent antidotes _in vivo_.[145]
[145] WINTER and BLYTH: _The Analyst_, 1877, p. 204; LACERDA: _Compt.
rend. de l'Acad. des Sciences_, XCIII, p. 466; CALMETTE: _Annal.
Instit. Pasteur_, VI, p. 175, and VIII, p. 278.
We shall not here enter upon a detailed study of the toxic albuminoid
principles of serpent-venoms; moreover, our knowledge is rather vague,
as it is, on a number of points. It will suffice us to know that, taken
altogether, the active albuminoids of these venoms are numerous, and
that each venom has its own particular active constituents, differing
according to the species and variety of the snake.
Each one of these substances acts more or less rapidly, and may be
associated with different principles which give rise to the variability
of the action of these toxic agents. Among these toxic albuminoids, the
most virulent appear to be true albumins and globulins, followed by
the nucleo-albumins, as we have already stated; there are also found
in venoms alkaloidal bases, but these principles are present only in
very slight quantity. These bases are but very slightly toxic compared
with the toxins that accompany them.
=Natural Immunity towards Serpent-venoms.=--Certain animals exhibit
a natural immunity toward snake-bites; among them are the snakes
themselves, the hog, the hedgehog, and the mongoos (an Egyptian rat);
the blood of these animals contains apparently an antitoxin.[146]
[146] _Compt. rend. de l'Acad. des Sciences_, CXXI, p. 745; JACODOT:
_Arch. de Médecine Navale_, VII, p. 390.
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