_Soluble Albumen._—This is obtained in the solid form by evaporating
to dryness, at a temperature which does not exceed 120°, the serum
of blood; the dry mass is yellow, transparent, hard, tough, and
contains, besides the albumen, the salts and some other constituents
of the blood in minute quantities; these are extracted by digestion
in alcohol and ether, which leave the albumen pure. When thus
completely dry it maybe heated beyond 212° without passing into the
coagulated condition; if digested in cold water it gradually swells
up and finally dissolves. This solution, when heated to a temperature
between 140° and 150°, coagulates; if dilute, the solution may even
be heated to 165° without coagulating, and when present in very small
quantity the albumen may not separate until the water boils.
When once coagulated in this manner, albumen is totally insoluble
in water; it is then changed into its second form. The solution
of albumen is precipitated by _alcohol_, by _acids_ and _metallic
salts_, exactly as the solution of fibrine in saltpetre; the only
distinction that can be drawn between the two is that the saline
solution of fibrine is partially decomposed by the addition of a
large quantity of water.
The precipitates yielded by a solution of albumen with metallic
salts are mixture of two distinct substances, one a compound of
albumen with the acid, the other a compound of albumen with the
metallic oxide; the former is generally somewhat soluble, the latter
insoluble, and hence results the application of albumen as an
antidote to mineral poisons, as corrosive sublimate and blue stone.
Albumen is also coagulated by many organic bodies, as tannic acid
and creosote, which acts catalytically, as a very minute quantity
of it coagulates a large quantity of albumen, without entering into
combination with it.
_Of the Gelatinous Constituents of the Tissues._—When the skin,
cellular or serous, tissues, tendons, and some forms of cartilage,
as that of bones, are boiled in water, they dissolve in great part
and form a solution which gelatinizes on cooling. Some of these
tissues, as the skin, dissolve easily and almost completely; others
dissolve but partly, and leave behind a quantity of coagulated
albumen. In most kinds of cartilage a very prolonged boiling is
necessary to extract a sensible quantity of gelatine. These various
tissues are thus found to consist of albumen and gelatine, united
in various proportions, and each presenting various degrees of
condensation of texture; but by boiling they may be completely
separated from each other.
Gelatine is insoluble in alcohol and ether. When a solution of
gelatine is long exposed to the air, it undergoes a commencement of
putrefaction, and loses its property of gelatinizing.
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