“Two tubes of serum containing micrococci were obtained from M. Toussaint, who holds that micrococci are the cause of the disease. Toussaint obtains the organisms by inoculation of flasks containing serum, or infusion of rabbit with the blood of tuberculous animals; and he has in some cases succeeded in producing tuberculosis by the injection of these cultivations into other animals. The material obtained from M. Toussaint was injected into three rabbits, two guinea-pigs, one cat, and one mouse, and of these seven animals six were under observation for a sufficient length of time for the development at least of local tuberculosis. In no instance did tuberculosis ensue. (In all the experiments detailed in this report inoculation was made into the anterior chamber of the eye whenever this was practicable; syringes purified by heat were employed for the purpose.) Cultivations of these micrococci were also made, and injected into nine rabbits, and three guinea-pigs. Of these, four rabbits and three guinea-pigs were under observation for a considerable time without the development of tuberculosis in any case. The total result is that thirteen animals were inoculated with the micrococci with which Toussaint works, and obtained from Toussaint himself, and in no case did tuberculosis occur.”--_Lancet_, March 17, 1883, pp. 444-5. “_Experiment. V., November 7th, 1882._--Experiment with pus from the wound of a patient suffering from pyæmia. The pus was thick and foul smelling. “1. One minim was injected _into the left eye_ of a rabbit. Panophthalmos [inflammation of the eye, involving every part of it] resulted and the animal was ill for some time. It, however, gradually recovered, and in December was apparently well. It died on January 10th, 1883. Lived 64 days.” (P. 267.) “_Experiment XIV., November 2nd, 1882._--The bacilli were rubbed up with boiled distilled water as usual. A little of the pure material was injected _into the right eyes_ of three rabbits. Into the _left eyes_ the following materials were injected:-- “No. 1.--One part of the fluid containing bacilli was mixed with one part of a 1 per 1,000 watery solution of bichloride of mercury. This mixture was allowed to stand for twelve minutes, and then injected into the left eye of No. 1. “_Result in No. 1._--On November 23rd, 1882, it was found there was a well-developed tubercular iritis [inflammation of the iris--the coloured part of the eye surrounding the pupil] in the right eye, but apparently nothing in the left. On December 10th, 1882, the left eye was beginning to show appearances of tubercular iritis; the right eye become converted into a caseous [cheese-like] mass. This animal died on January 7th, 1883. Lived 66 days.” (P. 285.)--“Report to the Association for the Advancement of Medicine by Research.”--_Practitioner_, April, 1883. =Chirone, Vincenzo.= Prof. at Palermo. Engaged with Curci in experiments on biological action of pirotoxine and cinchonidine.