The second Testimony is taken out of the last piece of his Age, and after the experience (as some think) of no less then an hundred years, that is, his book of Aphorisms, or short and definitive determinations in Physick. The Aphorism alleadged is this, _Sub Cane et ante Canem difficiles sunt purgationes._ _Sub Cane et Anticane_, say some including both the Dog-stars; but that cannot consist with the Greek: ὑπὸ κύνα καὶ πρὸ κυνὸς, nor had that Criticism been ever omitted by _Galen_. Now how true this sentence was in the mouth of _Hippocrates_, and with what restraint it must be understood by us, will readily appear from the difference between us both, in circumstantial relations. And first, Concerning his time and Chronology: [SN: _When_ Hippocrates _lived_.] he lived in the reign of _Artaxerxes Longimanus_, about the 82 Olympiade, 450 years before Christ; and from our times above two thousand. Now since that time (as we have already declared) the Stars have varied their longitudes; and having made large progressions from West to East, the time of the Dog-stars ascent must also very much alter. For it ariseth later now in the year, then it formerly did in the same latitude; and far later unto us who have a greater elevation; for in the daies of _Hippocrates_ this Star ascended in Cancer, which now ariseth in Leo: and will in progression of time arise in Virgo. And therefore in regard of the time wherein he lived, the Aphorism was more considerable in his daies then in ours, and in times far past then present, and in his Countrey then ours. The place of his nativity was _Coos_, an Island in the _Myrtoan_ Sea, not far from _Rhodes_, described in Maps by the name of _Lango_, and called by the _Turks_ who are Masters thereof, _Stancora_; according unto _Ptolomy_ of Northern latitude 36 degrees. That he lived and writ in these parts, is not improbably collected from the Epistles that passed betwixt him and _Artaxerxes_; as also between the Citizens of _Abdera_, and _Coos_, in the behalf of _Democritus_. Which place being seated from our latitude of 52, 16 degrees Southward, there will arise a different consideration; and we may much deceive our selves if we conform the ascent of Stars in one place unto another, or conceive they arise the same day of the month in _Coos_ and in _England_. For as _Petavius_ computes in the first _Julian_ year, at _Alexandria_ of latitude 31, the Star arose cosmically in the twelfth degree of Cancer, Heliacally the 26, by the compute of _Geminus_ about this time at _Rhodes_ of latitude 37, it ascended cosmically the 16 of Cancer, Heliacally the first of Leo; and about that time at _Rome_ of latitude 42, cosmically the 22 of Cancer, and Heliacally the first of Leo. For unto places of greater latitude it ariseth ever later; so that in some latitudes the cosmical ascent happeneth not before the twentieth degree of Virgo, ten daies before the Autumnal Equinox, and if they compute Heliacally, after it, in Libra.