The valves, in a word, do not invariably look upwards, but always towards the trunks of the veins--towards the seat of the heart. They are solely made and instituted lest, instead of advancing from the extreme to the central parts of the body, the blood should rather proceed along the veins from the centre to the extremities; but the delicate valves, while they readily open in the right direction, entirely prevent all such contrary motion, being so situated and arranged that if anything escapes, or is less perfectly obstructed by the flaps of the one above, the fluid passing, as it were, by the chinks between the flaps, it is immediately received on the convexity of the one beneath, which is placed transversely with reference to the former, and so is effectually hindered from getting any farther. And this I have frequently experienced in my dissections of veins. If I attempted to pass a probe from the trunk of the veins into one of the smaller branches, whatever care I took I found it impossible to introduce it far any way by reason of the valves; whilst, on the contrary, it was most easy to push it along in the opposite direction, from without inwards, or from the branches towards the trunks and roots. And now I may be allowed to give in brief my view of the circulation of the blood, and to propose it for general adoption. _The Conclusion_ Since all things, both argument and ocular demonstration, show that the blood passes through the lungs and heart by the action of the ventricles; and is sent for distribution to all parts of the body, where it makes its way into the veins and pores of the flesh; and then flows by the veins from the circumference on every side to the centre, from the lesser to the greater veins; and is by them finally discharged into the _vena cava_ and right auricle of the heart, and this in such a quantity or in such a flux and reflux, thither by the arteries, hither by the veins, as cannot possibly be supplied by the ingesta, and is much greater than can be required for mere purposes of nutrition; therefore, it is absolutely necessary to conclude that the blood in the animal body is impelled in a circle and is in a state of ceaseless motion; and that this is the act, or function, which the heart performs by means of its pulse, and that it is the sole and only end of the motion and contraction of the heart. For it would be very difficult to explain in any other way to what purpose all is constructed and arranged as we have seen it to be. SIR JOHN HERSCHEL Outlines of Astronomy