The traveller who ascends to the lofty plateau of the Cordilleras cannot fail to be deeply interested in the former history and melancholy fate of the Peruvian Indians; and some account of their condition under Spanish colonial rule, and of the insurrection of Tupac Amaru, the last of the Incas, will, I trust, not be unwelcome. I have devoted three chapters to these subjects, which will form a short digression on our way to the Chinchona forests. I am indebted to the late General Miller, and to Dr. Vigil, the learned Director of the National Library at Lima, for much new and very curious material throwing light on that period of Spanish colonial history which includes the great rebellion of the Peruvian Indians in 1780. The second part of the work contains a narrative of my travels in India, a description of the sites selected for Chinchona-plantations, and an account of the progress of the experimental cultivation of those inestimable trees, from the arrival of the plants and seeds, early in 1861, to the latest dates. In conducting the operations connected with the collection of Chinchona-plants and seeds in South America, I obtained the services of Mr. Spruce, Mr. Pritchett, Mr. Cross, and Mr. Weir; and it affords me great pleasure to have this opportunity of publicly recording their perseverance in facing many dangers and hardships, and in doing the work that was allotted to them so ably, and with such complete success. To Mr. Richard Spruce, an eminent botanist who has for eight years been engaged in exploring the basin of the Amazons, from Para to the peaks of the Quitenian Andes, and from the falls of the Orinoco to the head-waters of the Huallaga, the largest share of credit, so far as the South American portion of the enterprise is concerned, undoubtedly belongs. I have endeavoured to do justice to his untiring energy and zeal, and to the important service which he has rendered to India. But the collection of plants and seeds in South America, and their conveyance to the shores of India, would have been of little use if they had not been delivered into competent hands on arriving at their destination. To the scientific and practical knowledge, the unwearied zeal, and skilful management of Mr. McIvor, the Superintendent of the Government Gardens at Ootacamund, on the Neilgherry hills, is therefore due the successful introduction of Chinchona-plants into India. His care has now been fully rewarded, and the experiment has reached a point which places it beyond the possibility of ultimate failure.