Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physicChristison, Robert, Sir
Science
Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physic
Christison, Robert, Sir
Medical jurisprudence; Toxicology
Iodine and iodide of potassium in medicinal doses have been supposed by
Dr. Lawrie to be capable of exciting in certain constitutions an
affection resembling _cynanche laryngea_ in its symptoms, consisting of
inflammation of the salivary glands, glottis, and other adjacent parts,
and proving sometimes fatal.[355] This property is doubtful; but several
instances have been published of profuse salivation and soreness of the
mouth during a course of iodine; it is apt to cause chronic irritation
of the Schneiderian membrane; and some think that it may affect in like
manner the bronchial membrane in the lungs.[356]
_Morbid Appearances from Iodine._—The only account I have seen of the
appearances left in the body after death from slow poisoning with iodine
is contained in the essay of Dr. Zink. In a second fatal case which came
under his notice he found enlarged abdomen from distension of the
intestines with gases, enlargement of the other viscera and serous
effusion into the peritonæum; adhesion of the viscera to one another;
redness of the intestines, in some places approaching to gangrenous
discoloration; redness and excoriation of the peritonæal coat of the
stomach, and also of its villous coat; enlargement and pale rose-red
coloration of the liver. In the chest serum was found in the sac of the
pleura. The gullet was contracted in diameter, and red internally.
ON POISONING WITH IODIDE OF POTASSIUM.
To these remarks on iodine a few observations may be added on the iodide
of potassium, one of its compounds, which is now generally substituted
in medicine for the simple substance. The tests and actions of this
poison have been examined by M. Devergie; and more lately its
medico-legal chemistry has been investigated by Dr. O’Shaughnessey and
Professor Orfila.
It is sold in the shops of various degrees of purity. Pure iodide of
potassium is in white crystals, tending to the cubical form, permanent
in the air, possessing a faint peculiar odour, and easily soluble in
both water and rectified spirit. Another variety has the same form, but
possesses an odour of iodine, is often yellowish in colour, and
deliquesces slightly in moist air. This contains an excess of iodine,
but may be otherwise pure. A third variety is impure. It presents less
tendency to assume a crystalline form, is more or less deliquescent,
dissolves but partially in alcohol, and when dissolved effervesces with
acids. The principal ingredient in this article is carbonate of potass;
and sometimes the proportion of iodide is inconsiderable. In one
specimen I procured 74·5 per cent. of carbonate of potass, 16 of water,
and only 9·5 of iodide of potassium.
In the solid state the iodide of potassium may be known by the effect of
strong sulphuric or nitric acid, which turns it brown with
effervescence, and when aided by heat disengages violet fumes of iodine.
Public-domain text, read in full here on John Shaqi.
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