Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physicChristison, Robert, Sir
Science
Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physic
Christison, Robert, Sir
Medical jurisprudence; Toxicology
Hospital of Pavia got each an ounce of nitre by mistake for sulphate of
magnesia. Two, who vomited immediately, did not suffer. The third, who
retained the salt fifteen minutes, had pain in the stomach and vomiting,
followed by paleness of the countenance, stiffness of the jaw, some
stupor, and convulsive movements of the limbs; which symptoms continued
till next day, when she gradually recovered.[462] A German physician,
Dr. Geiseler, met with an instance, in which the only disorder produced
appeared to depend on derangement of the cerebral functions. A woman,
after swallowing an ounce of nitre instead of Glauber’s salt, lost the
use of speech and the power of voluntary motion, then became insensible,
and was attacked with tetanic spasms. This state lasted till next day,
when some amelioration was brought about by copious sweating. It was
not, however, till eight days after, that she recovered her speech, or
the entire use of her mental faculties; and the palsy of the limbs
continued two months.[463] Her case resembles the account given by
Orfila of the effects of nitre on animals.
SECTION III.—_Of the Morbid Appearances caused by Nitrate of Potass._
The morbid appearances observed in man are solely those of violent
inflammation of the stomach and intestines. In Laflize’s case, which
proved fatal in three hours, the stomach was distended, and the contents
deeply tinged with blood; its peritonæal coat of a dark-red colour
mottled with black spots; its villous coat very much inflamed and
detached in several places. The liquid contents gave satisfactory
evidence of nitre having been swallowed; for a portion evaporated to
dryness deflagrated with burning charcoal. In Souville’s patient, who
lived sixty hours, the stomach was every where red, in many places
checkered with black spots, and at the centre of one of these spots the
stomach was perforated by a small aperture. The whole intestinal canal
was also red. In Dr. Geoghegan’s case, the stomach contained bloody
mucus, and its villous coat was brownish-red, and here and there
detached. He could not detect any nitre in it.
CHAPTER IX.
OF POISONING WITH THE ALKALINE AND EARTHY CHLORIDES.
There can be little doubt that the _chlorides_ of _soda_, _potass_, and
_lime_ are active poisons; but the first two have alone been hitherto
carefully investigated by physiological experiments.
The two alkaline chlorides are usually seen in the form of colourless
solutions. That of potass is little known in this country; but that of
soda is familiar to all in the shape of Fincham’s chloride of soda or
bleaching liquid. The chloride of lime, which is best known of them all,
is usually in the form of a dry powder, deliquescent, and acrid,
commonly termed bleaching powder. All these substances are easily known
by their peculiar odour of chlorine, and the copious disengagement of
that gas on the addition of sulphuric acid.
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