Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physicChristison, Robert, Sir
Science
Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physic
Christison, Robert, Sir
Medical jurisprudence; Toxicology
The action of chloride of soda on the animal body has been examined by
Segalas, who infers that it is an irritant poison, which, however, at
times occasions symptoms of an affection of the nervous system. He
remarked that three ounces of the solution, commonly sold in Paris under
the name of Labarraque’s disinfecting liquid, caused immediate death by
coagulating the blood in the heart, when injected into a vein in a dog.
Two ounces introduced into the peritonæum excited palpitation, oppressed
breathing, constant restlessness, and death in ten minutes; and three
drachms did not prove fatal for some hours, tetanic spasms being
produced in the first instance, and peritonæal inflammation being found
after death. One ounce introduced into the stomach of a dog excited
immediate vomiting, and no farther inconvenience; and two ounces
retained by a ligature on the gullet brought on violent efforts to
vomit, from which the animal was gradually recovering, when it was
killed in twenty-four hours for the sake of observing the appearances.
The stomach was found generally inflamed and interspersed with dark,
gangrenous-like spots.[464]
I am not acquainted with any case of poisoning with these substances in
the human subject. But it is probable that symptoms of pure irritation
and inflammation will occur, and that moderate doses may prove fatal.
CHAPTER X.
OF POISONING WITH LIME.
Lime, the last poison of the present group, is a substance of little
interest to the toxicologist, as its activity is not great.
Its physical and chemical properties need not be minutely described. It
is soluble, though sparingly, in water; and the solution turns the
vegetable blues green, restores the purple of reddened litmus, gives a
white precipitate with a stream of carbonic acid gas, and with oxalic
acid a very insoluble precipitate, which is not redissolved by an excess
of the test.
Its action is purely irritant. Orfila has found that a drachm and a half
of unslaked lime, given to a little dog, caused vomiting and slight
suffering for a day only, but that three drachms killed the same animal
in five days, vomiting, languor, and whining being the only symptoms,
and redness of the throat, gullet, and stomach, the only morbid
appearances.[465]
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