Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physicChristison, Robert, Sir
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Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physic
Christison, Robert, Sir
Medical jurisprudence; Toxicology
The present is by far the most important of the conditions under which
it may be necessary to search for arsenic in medico-legal cases; for in
nine cases out of ten the subject of analysis is either some article of
food or drink, the contents or tissues of the stomach, or the textures
of other organs of the body into which the poison has been carried by
absorption.
Accordingly much attention has been paid to this subject for some years
past, and many valuable methods of analysis have been suggested, more
especially since the recent discovery that arsenic, like many other
poisons, undergo absorption, and is diffused by the circulation
throughout the body generally. It was proved by me in 1824,[531] that
the tests for arsenic, at that time in general use, are so fallacious
when applied to complex organic mixtures as to be unfit for medico-legal
investigations except merely as trial-tests; and a process was proposed,
which has since undergone various modifications from others as well as
myself. This process, in the form in which it was adopted in the last
edition of the present work, is still applicable to a great proportion
of cases; and indeed a recent modification of it has been thought by
Drs. Fresenius and von Babo to be superior even yet to every other in
all circumstances.[532] But two new methods are at present generally
preferred, and probably not without reason. At least they have been much
employed and with great success in numerous medico-legal researches,
where the quantity of arsenic was to all appearance extremely small, and
the subject of examination most complex and troublesome to bring within
the sphere of analysis. And in particular they have been successfully
employed to detect arsenic in those organs of the human body into which
it can obtain admission only through the medium of absorption.
In the following statement I shall describe four processes only, that of
Reinsch, by which the arsenic is first separated as a crust on
copper,—that of Marsh, who first detaches it in the form of
arseniuretted-hydrogen,—my own method, which consists in obtaining in
the first instance a sulphuret of arsenic,—and that of Drs. Fresenius
and von Babo, which has the same foundation.
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