Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physicChristison, Robert, Sir
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Treatise on Poisons: In relation to medical jurisprudence, physiology, and the practice of physic
Christison, Robert, Sir
Medical jurisprudence; Toxicology
Dehaen relates a distinct example of this disorder occurring in a female
who took a small quantity of arsenic by mistake. The ordinary signs of
inflammation were soon subdued, and for three days she did well; but on
the fourth she was attacked with cramps, tenderness, and weakness of the
feet, legs and arms, increasing gradually till the whole extremities
became at length almost completely palsied. At the same time the cuticle
desquamated. But the other functions continued entire. The power of
motion returned first in the hands, then in the arms, and she eventually
recovered; but eleven months passed before she could quit the hospital
where Dehaen treated her.[663]
An excellent account of a set of similar cases has been given by Dr.
Murray of Aberdeen. They became the subject of judicial inquiry on the
trial of George Thom, who was condemned in 1821 at the Aberdeen autumn
circuit for poisoning his brother-in-law. Four persons were
simultaneously affected about an hour after breakfast with the primary
symptoms of poisoning with arsenic, and some in a very violent degree.
But besides these symptoms, in all of them the muscular debility was
great; and in two it amounted to true partial palsy. One of them lost
altogether the power of the left arm, and six months after, when the
account of the cases was published, he was unable to bend the arm at the
elbow-joint. The other had also great general debility and
long-continued numbness and pains of the legs.[664]
An interesting case of the same nature with these was lately submitted
to me on the part of the crown. A man after taking arsenic was attacked
with vomiting, purging, and other symptoms of abdominal irritation,
which were mistaken for dysentery. Five days afterwards he began to
suffer also from feebleness of the limbs; amounting almost to palsy.
Subsequently an improvement slowly took place; but he continued to
suffer under irritative fever, diarrhœa, and faintness. Several weeks
later the diarrhœa abated, but he had great stiffness, numbness, and
loss of power in the joints of the hands and feet. Two months after he
first took ill, and while he was slowly recovering from this paralytic
affection, arsenic was again administered and proved fatal in eighteen
hours.
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