Nevertheless, it is singular how ineffectual vomiting proves in expelling some poisons from the stomach. Those which are not easily soluble, and have been taken in a state of minute division, may remain adhering to the villous coat, notwithstanding repeated and violent efforts to dislodge them by vomiting. Many instances to this effect have occurred in the instance of arsenic. Metzger has related a case, where, after six hours of incessant vomiting, three drachms were found in the stomach.[90] Mr. Sidey, a surgeon of this city, has mentioned to me an instance of poisoning with king’s yellow, in which he found the stomach lined with the poison, although the patient had vomited for thirty hours. In three cases which I have investigated arsenic was detected, although the people lived and vomited much for nearly two days;[91] and Professor Orfila has noticed a similar instance in which that poison was found in the contents of the stomach, although the person had vomited incessantly for two entire days.[92] It is not easy to specify the period after which a poison that has excited vomiting need not be looked for in the stomach. It must vary with a variety of circumstances whose combined effect it is almost impossible to appreciate, such as the solubility and state of division of the poison, the frequency of vomiting, the substances taken as remedies, and the like. When the poison is in solution and the patient vomits much, an analysis may be expected to prove frequently abortive, even though the individual survives but a few hours, as in Mr. Hewson’s case already noticed. In other circumstances, however, as various facts quoted above will show, poisons may frequently be found after two days incessant vomiting; and on the whole it may be stated, that the recent improvements in analysis render the period much longer than it has generally been, and would naturally be imagined. Metzger has related the case of a woman poisoned with arsenic mixed with currants, in whose body, after eight days of frequent vomiting, he found ten or twelve currants, which gave out an odour of garlic when burnt;[93] but here the dose, if there was really arsenic, must have been repeated recently before death, for it is not possible to conceive how currants could remain in the stomach so long, whatever may be thought of the possibility of arsenic remaining. It is farther proper to add, that Professor Henke of Erlangen, one of the highest living authorities in Germany, once found grains of arsenic in the gullet, although he found none in any other part of the body, of a person who survived the taking of the poison four days.[94] Allowing to this fact all the weight derived from the high name of its author, I must nevertheless express great doubt whether the arsenic was not repeated more recently before death.