2. The poison may have disappeared, because it has been all absorbed. It has several times happened that in the bodies of those poisoned with laudanum, or even with solid opium, none of the drug could be detected after death. Sometimes indeed it is found, even though the individual survived the taking of the poison many hours. Thus a case related by Meyer of Berlin, in which the person lived ten hours after taking the saffron-tincture of opium; and nevertheless it was detected in the stomach by a mixed smell of saffron and opium.[95] But more commonly it all disappears, unless the dose has been very large. In a case of poisoning with laudanum, which I examined here along with Sir W. Newbigging in 1823, none could be detected, although strong moral circumstances left no doubt that laudanum had been swallowed seven or eight hours before death. An instance of the same kind has been minutely related by Pyl. It was that of an infant who was poisoned with a mixture of opium and hyoscyamus, and in whose stomach and intestines none could be detected by the smell.[96] Similar observations have been often made on animals; and several additional cases of the same purport, occurring in man, will be related under the head of opium. It might be of use to quote some of the numerous errors committed by medical witnesses, in consequence of having overlooked the effect of absorption in removing poisons beyond the reach of chemical analysis. But not to be too prolix, I shall be content with mentioning a single very distinct case in point, which happened at a Coroner’s Inquest in London, in 1823. A young man one evening called his fellow-lodger to his bedside; assured him he had taken laudanum, and should be dead by the morrow; and desired him to carry his last farewell to his mother and his mistress. His companion thought he was shamming; but next morning the unfortunate youth was found in the agonies of death. The moral evidence was not very satisfactory; but that is of little consequence to my present object. The point in the case I would particularly refer to is the declaration of the medical inspector, that laudanum could not have been taken, because he did not find any by the smell or by chemical analysis in the contents of the stomach.[97] 3. Poisons may not be found, because the excess has been decomposed. Vegetable and animal poisons may be altogether destroyed by the process of digestion. This observation will explain why sometimes no poison could be found in cases of poisoning with crude opium or other vegetable solids. A French physician, M. Desruelles, has related the case of a soldier, who died six hours and a half after swallowing two drachms of solid opium, and in whose stomach nothing was found but a yellowish fluid, quite destitute of the smell of the drug.[98]