The correspondence in point of time between the appearance of symptoms of poisoning, and the administration of suspicious articles by an individual, constitutes still more decisive proof in a set of cases, in which it is of great value, as the chemical evidence is generally defective,—namely, where poisoning is attempted with repeated moderate doses. If the several renewals or exacerbations of illness correspond with the periods when suspicious articles have been given by the same individual, the circumstantial evidence of the administration may be even tantamount to direct proof. Thus, on the trial of Miss Blandy for the murder of her father, it was proved, that Mr. Blandy on several occasions, after the prisoner received certain suspicious powders from her lover, was taken ill with vomiting and purging; and that on two occasions recently before his death, when he got from his daughter a bowl of gruel which contained a gritty sediment, he was attacked after a very short interval with pricking and heat in the throat, mouth, stomach, and bowels,—with sickness, vomiting, gripes, and bloody diarrhœa.[127] Here the proof of administration by the prisoner was complete. These examples will show how the evidence of a particular person’s criminality may be affected by the relation subsisting in point of time between the commencement of the symptoms and the suspicious administration of particular articles. But farther, the special period at which the symptoms begin may even at times supply strong evidence of his instrumentality, although there may be no direct proof from general evidence of his having been concerned in administering anything whatever in a suspicious manner. This statement is well exemplified by the case of Mrs. Humphreys, who was convicted at the Aberdeen Autumn Circuit in 1830 for poisoning her husband, by pouring sulphuric acid down his throat while he was asleep. It was clearly proved, as will be seen under the head of sulphuric acid, that the deceased died of this poison; and the administration was brought home to the prisoner in the following singular manner. The only inmates of the house were the deceased, the prisoner, and a maid-servant. The deceased got a little intoxicated one evening at a drinking party in his own house; and after his friends all left the house, and the street-door was barred inside, he went to bed in perfect health, and soon fell fast asleep. But he had slept scarcely twenty minutes, when he suddenly awoke with violent burning in his throat and stomach; and he expired in great agony towards the close of the second day. Now sulphuric acid, when it occasions the violent symptoms observed in this instance, invariably excites them in a few seconds, or in the very act of swallowing. It was, therefore, impossible that the man could have received the poison at the time he was drinking with his friends; and as he knew he had not taken any thing else