The alleged purpose of these experiments was to discover an effective treatment for the burns caused by mustard gas. In 1944 the experiments were coordinated with a general program for research into gas warfare. A decree issued by Hitler in March 1944 ordered the defendant Karl Brandt to push medical research in connection with gas warfare. The defendant Rudolf Brandt sent copies of this decree to the defendant Sievers, to Grawitz, and others, and transmitted Hitler’s request that they confer soon with the defendant Karl Brandt “on account of the urgency of the order given him by the Fuehrer.” Subsequently, Sievers, who was thoroughly familiar with the mustard gas experiments being carried on in the concentration camps, reported the details of these experiments to the defendant Karl Brandt. E. and F. Ravensbrueck Experiments Concerning Sulfanilamide and Other Drugs; Bone, Muscle, and Nerve Regeneration and Bone Transplantation The experiments conducted principally on the female inmates of Ravensbrueck concentration camp were perhaps the most barbaric of all. These concerned bone, muscle, and nerve regeneration and bone transplantation, and experiments with sulfanilamide and other drugs. They were carried out by the defendants Fischer and Oberheuser under the direction of the defendant Gebhardt. In one set of experiments, incisions were made on the legs of several of the camp inmates for the purpose of simulating battle-caused infections. A bacterial culture, or fragments of wood shavings, or tiny pieces of glass were forced into the wound. After several days, the wounds were treated with sulfanilamide. Grawitz, the head of the SS Medical Service, visited Ravensbrueck and received a report on these experiments directly from the defendant Fischer. Grawitz thereupon directed that the wounds inflicted on the subjects should be even more severe so that conditions similar to those prevailing at the front lines would be more completely simulated. Bullet wounds were simulated on the subjects by tying off the blood vessels at both ends of the incision. A gangrene-producing culture was then placed in the wounds. Severe infection resulted within 24 hours. Operations were then performed on the infected areas and the wounds were treated with sulfanilamide. In each of the many sulfanilamide experiments, some of the subjects were wounded and infected but were not given sulfanilamide, so as to compare their reactions with those who received treatment.