Every man, who believes that the path of virtue is thorny, and that of vice is pleasurable, is not only deceived, but has not yet learned that the Most High holds the reins of government, and dispenses to his creatures their rewards and punishments. It is evident, if every man solemnly believed that a course of sin would bring upon him certain and unavoidable misery--and that every species of dishonesty would lessen his fortune in the world, he would abandon his course, and turn his feet to the testimonies of God. The transgressor is therefore deceiving himself, is resting under a strong delusion, and is yet ignorant that the Almighty rules throughout his vast dominions. Certain it is that a wicked man was never happy while remaining in that condition, and it is equally certain that no one ever yet went unpunished. To this point we intend to invite your serious attention in this discourse. The expression in our text, "till thou know that the Most High ruleth in the kingdom of men," does not only imply a knowledge of the existence of a Supreme Intelligence, who governs the world, but an obedience to the moral laws of his empire. On this proposition we purpose to offer a few rational, and not only rational, but irresistible arguments. We will first notice the condition of those who are guilty of heinous crimes, and then come down to the common walks of life, and bestow a few remarks on those who are indifferent about their condition, and only guard their conduct so far as comports with the customs and manners of that portion of the community, who have no higher principle of action than to be considered respectable among men. Though we come before the public to defend the doctrines of Christ, yet, my friends, you will bear in mind that it is also our duty to enforce his precepts, and exhort to the obedience of the gospel. That we should point out the road of sin, error and misery, and also endeavor to throw the light of heavenly truth on the pathway of human life. We will begin with the murderer, who wantonly embrues his hands in the blood of his fellow. So far as he has violated the laws of his country, he is a subject for public execution, and has nothing to hope for, at the tribunal of human justice. His misery, whether it arise from the contemplation of an ignominious death, from the fear of detection, or from the consciousness of having violated the moral principles of his nature, is alike insupportable, as well as indescribable.