[1] Professor Crookshank, in his evidence before the Royal Commission (4th Report, Q. 11,729) quotes Dr. De Haën, a writer on Inoculation, as saying: “Asthma, consumption, hectic or slow fever of any kind, internal ulcers, obstructed glands, obstructions of the viscera from fevers, scrofula, scurvy, itch, eruptions, local inflammations or pains of any kind, debility, suppressed or irregular menstruation, chlorosis, jaundice, pregnancy, _lues venerea_, whether in the parent or transmitted to the child, and a constitution under the strong influence of mercury, prevented the operation.” There is no evidence that those who applied the so-called “variolous test” in the early days of vaccination paid any attention to this long list of ailments, many of which were very prevalent at the time, and which would, in the opinion of De Haën, and of the English writer Sanders, who quotes him, have prevented the action of the virus and thus rendered the “test” entirely fallacious. With such causes as these, added to those already discussed, it becomes less difficult to understand how it was that the alleged test was thought to prove the influence of the previous vaccination without really doing so. [2] The cases of failure of vaccination here referred to are given in Mr. William White’s _Story of a Great Delusion_, where fuller extracts and references will be found. [3] These extracts from the Reports are given by Mr. White in his _Story of a Great Delusion_. The actual deaths from small-pox during the last century are given in the Second Report of the Royal Commission, p. 290. The above statements have been verified at the British Museum by my friend Dr. Scott Tebb, and are verbally accurate. [4] As an example of the dreadful results of vaccination, even where special care was taken, the following case from the Sixth Report of the Royal Commission (p. 128) is worthy of earnest attention. It is the evidence of Dr. Thomas Skinner, of Liverpool: