_Q._ 20,766. Will you give the Commission the particulars of the case?—A young lady, fifteen years of age, living at Grove Park, Liverpool, was revaccinated by me at her father’s request, during an outbreak of small-pox in Liverpool in 1865, as I had revaccinated all the girls in the Orphan Girls’ Asylum in Myrtle Street, Liverpool (over 200 girls, I believe), and as the young lady’s father was chaplain to the asylum, he selected, and I approved of the selection, of a young girl, the picture of health, and whose vaccine vesicle was matured, and as perfect in appearance as it is possible to conceive. On the eighth day I took off the lymph in a capillary glass tube, almost filling the tube with clear, transparent lymph. Next day, 7th March, 1865, I revaccinated the young lady from this same tube, and from the same tube and at the same time I revaccinated her mother and the cook. Before opening the tube I remember holding it up to the light and requesting the mother to observe how perfectly clear and homogeneous, like water, the lymph was, neither pus nor blood corpuscles were visible to the naked eye. All three operations were successful, and on the eighth day all three vesicles were matured “like a pearl upon a rose petal,” as Jenner described a perfect specimen. On that day, the eighth day after the operation, I visited my patient, and to all appearance she was in the soundest health and spirits, with her usual bright eyes and ruddy cheeks. Although I was much tempted to take the lymph from so healthy a vesicle and subject, I did not do so, as I have frequently seen erysipelas and other had consequences follow the opening of a matured vesicle. As I did not open the vesicle that operation could not be the cause of what followed. Between the tenth and the eleventh day after the revaccination—that is, about three days after the vesicle had matured and begun to scab over—I was called in haste to my patient the young lady, whom I found in one of the most severe rigors I ever witnessed, such as generally precedes or ushers in surgical, puerperal, and other forms of fever. This would be on the 18th March, 1865. Eight days from the time of this rigor my patient was dead, and she died of the most frightful form of blood poisoning that I ever witnessed, and I have been forty-five years in the active practice of my profession. After the rigor, a low form of acute peritonitis set in, with incessant vomiting and pain, which defied all means to allay. At last stercoraceous vomiting, and cold, clammy, deadly sweats of a sickly odour set in, with pulselessness, collapse, and death, which closed the terrible scene on the morning of the 26th March, 1865. Within twenty minutes of death rapid decomposition set in, and within two hours so great was the bloated and discoloured