Attracted by the reports of the first expedition, various merchants and adventurers had settled in the Coro country, and lived on good terms with the Caiquetia nation of Indians. Now, however, some of these colonists, losing taste for a civilised life, made attempts to commence the nefarious trade which was at that time disgracing all the countries of the Old World in Africa and America. Having learned wisdom from the disasters in Nueva Andalusia, the audience of Santo Domingo dispatched a splendid man in Juan de Ampies to nip the evil in the bud; as a first step he founded the city of Santa Ana de Coro on that Saint’s day in 1527, and in his administration sought steadily to foster the spirit of amity between the Caiquetias (under their cacique Manaure) and the Europeans. His good work was soon, however, destined to be ignored and frustrated by the selfish policy of the King of Spain. Charles V. had at various times raised heavy loans from the _Welser_, the bankers of Augsburg, and now in part payment he handed over to them the administration and exploitation of the newly-acquired province of Venezuela. Ambrosius Alfinger was appointed first Governor of Coro, with jurisdiction over all the country between the Gulf of Coquibacoa and the western end of the Peninsula of Paria. He arrived at the seat of his government with three hundred Spaniards, many of them of noble blood, and fifty German miners, and found Juan de Ampies too patriotic to raise difficulties on account of the ingratitude of a worthless king. The man who had founded Coro and started administration on sound lines spent the remainder of his days in retirement in Santo Domingo, though at a later date the barren island of Curaçao was given to him as some return for his services. The following year saw Nueva Andalusia constituted a definite province, under Don Diego de Ordaz as first Governor, who was given authority to explore and conquer all the territory to the south. Sedeño was appointed Governor of Trinidad, but as yet the Orinoco region was ignored or by implication included in New Andalusia, and it was therefore Ordaz who, upon his arrival, journeyed up the Orinoco as far as the rapids of Carichana, near the mouth of the Meta, where he heard stories of the gold and emeralds to be found in the country whence that river flowed. The success of the voyage proved his death, however, for Sedeño was jealous of his fame and in league with Matienza, then commander-in-chief in Cubagua, managed to poison Ordaz in Nueva Cadiz on his return.