Venoms: Venomous Animals and Antivenomous Serum-therapeuticsCalmette, A. (Albert)
Science
Venoms: Venomous Animals and Antivenomous Serum-therapeutics
Calmette, A. (Albert)
Antitoxins; Poisonous snakes; Toxins; Venom
“Cock’s flesh, applied while still warm, neutralises the venom of
snakes. The brains of the bird, swallowed in wine, produce the same
effect. The Parthians, for this purpose, make use of chicken’s brains.
The fresh flesh of the pigeon and the swallow, and owls’ feet burned,
are good against snake-bites.
“If one has been bitten by a snake or by any venomous animal, another
method of cure is to take salt fish and wine from time to time, so as
to vomit in the evening. This remedy is chiefly efficacious against
the bite of the _Chalcis_, _Cerastes_, _Seps_, _Elaps_ and _Dipsas_.”
* * * * *
In Equatorial America, and especially in India, a multitude of plants
are credited with marvellous properties, which they possess only in
the imagination of the snake-charmers or medicine-men by whom they are
employed. None of them stand the test of experiment, any more than the
more or less compound drugs, numbers of specimens of which from all
sources have passed through my hands.
It cannot, however, be denied that certain chemical substances, of
well-defined composition, are very useful, not as physiological
antidotes to venoms, but as agents for their modification or
destruction in the poisoned wounds, when they have not yet been
absorbed. In this way _permanganate of potash_, _chromic acid_,
_chloride of gold_, and the _alkaline hypochlorites_, especially
_hypochlorite of lime_, may be extremely useful under many
circumstances.
_Permanganate of potash_ was recommended in 1881 by Professor de
Lacerda,[104] of Rio de Janeiro, as the result of experiments made by
him with venoms of Brazilian snakes. When a few cubic centimetres of
a 1 per cent. solution of permanganate of potash are quickly injected
into the actual wound caused by the bite and around the point of
inoculation, there can be no doubt that the venom not yet absorbed is
destroyed. When mixed _in vitro_ with venom, permanganate renders the
latter innocuous.
Here, however, it is a case of actual destruction by direct contact. If
we inject a lethal dose of venom into the right thigh of an animal, for
example, and several cubic centimetres of permanganate solution into
different parts of the body, or beneath the skin of the left thigh,
neither the general intoxication nor the local effects of the venom are
modified.
The same may be said with regard to _chromic acid_ (1 per cent.
solution), recommended by Kaufmann[105] for the bite of the common
viper.
No other effect is produced by a 1 per cent. solution of _chloride of
gold_, or the _alkaline hypochlorites_, which I have shown to possess
a strong oxidising action on the different venoms, even on those that
are most rapidly diffusible, such as cobra-venom (see Chapter V.). They
possess, however, owing to their slight causticity, the advantage of
not producing severe local disorders, and in this respect they are to
be preferred.
Public-domain text, read in full here on John Shaqi.
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