SPIRITUS AETHERIS COMPOSITUS--COMPOUND SPIRIT OF ETHER--HOFFMAN’S ANODYNE Composed of ether, 325 parts; alcohol, 650 parts; ethereal oil, 25 parts. DOSE.--Same as for ether. ACTIONS.--Ether is anodyne, antispasmodic, diaphoretic, anthelmintic; a cardiac, respiratory and cerebral stimulant, an anesthetic and a narcotic poison; one of the best and quickest acting, diffusible, general stimulants, acting on the heart reflexly from the stomach. It is a powerful secretory stimulant, acting especially on the secretions of the stomach, salivary glands and pancreas. On the cerebrum and the motor and sensory nerves, its actions are similar to that of alcohol, but more prompt and less protracted; it is eliminated quickly, chiefly by the lungs. When inhaled, it first causes irritation of the fauces, a sense of strangulation and cough, then a stage of excitement in which the visible mucous membranes are flushed and the respiration and pulse quickened; a convulsive stage generally follows, with rigid muscles and respiration stertorous; this subsides and complete insensibility is established, the muscles being relaxed and the reflexes abolished; in fact all of the functions of the body are suspended, except respiration and circulation. If the inhalation be continued these too become paralyzed, death usually resulting from slow paralysis of respiration (chloroform paralyzes quickly); the heart pulsating long after breathing has ceased. Atropine hypodermically is the best antagonist to the toxic effects of ether, also artificial respiration and injections of brandy.