In the second series of experiments twenty-eight animals were sacrificed, some of them taken from nursing their young, exposed to torture for an hour or two, then allowed to rest an hour, and usually replaced in the machine to be crushed or torn by the Professor for periods of from two to six hours more. In the table wherein these experiments are summed up, the terms _molto dolore_ and _crudeli dolori_ are delicately distinguished, the latter being apparently reserved for the cases when the victims were, as the Professor expresses it, _lardellati di chiodi_--("larded with nails"). In conclusion, the author informs us (p. 25) that these experiments were all conducted "_con molto amore e pazienza!_"--with much zeal and patience. I am, etc., FRANCES POWER COBBE. In a controversy with Dr. Pye-Smith, who had read a paper before the British Association, Miss Cobbe writes as follows to one of the public journals: "Dr. Pye-Smith is reported to have said: 'Happily, the neccessary experiments were comparatively few.' Few! What are a "few" experiments? Professor Schiff in ten years experimented on 14,000 dogs, given over to him by the Municipality of Florence, and returned their carcases so mangled that the man who had contracted for their skins found them useless. He also experimented on pigeons, cats, and rabbits to the number, it is calculated, of 70,000 creatures; and he now asks for ten dogs a week in Geneva. All over Germany and France there are laboratories "using" (as the horrible phrase is) numberless animals, inasmuch as I have just received a letter stating that dogs are actually becoming scarce in Lyons, and it is proposed to breed them for the purpose of Vivisection. Be this true or not, I invite any of your readers to visit the office of the Victoria Street Society, and examine the volumes of splendid plates of vivisecting instruments, which will there be shown them, and then judge for themselves whether it be for a few experiments that those elaborate and costly inventions have become a regular branch of manufacture. Let them examine the volume of the English handbook of the physiological laboratory, the volume of Cyon's magnificent atlas, with its 54 plates, the _Archives de Physiologie_, with its 191 plates, the _Physiologische Methodik_, or Claude Bernard's _Lecons sur la Chaleur Animale_, with its pictures of the stoves wherein he baked dogs and rabbits alive; and after these sights of disgust and horror they will know how to understand the word "few" in the vocabulary of a physiologist. I am glad to hear that a German opponent of Vivisection recently entering a shop devoted to the sale of these tools of torture, was greeted by the proprietor with a volley of abuse: 'It is you and your friends,' he said, 'who are destroying my trade. I used to sell a hundred of Czermak's tables and other instruments for one I sell now.'