Assuming that by vivisection benefits might be obtained for human bodies, we hold that the evil results of the practice on human minds would more than counterbalance any such benefits. The cowardice and pitilessness involved in tying down a dog on a table and slowly mangling its brain, its eyes, its entrails; the sin committed against love and fidelity themselves when a creature capable of dying of grief on his master's grave is dealt with as a mere parcel of material tissues, "valuable for purposes of research"--these are basenesses for which no physical advantages would compensate, and the prevalence of such a heart-hardening process among our young men would, we are convinced, detract more from the moral interests of our nation than a thousand cases of recovery from disease would serve those of a lower kind. Even life itself ought not to be saved by such methods, any more than by the cannibalism of the men of the "Mignonette." Our second answer is yet more brief. We do not "deny that the benefit of man is a sufficient justification for inflicting pain upon animals," provided that pain is kept within moderate bounds, nor yet to taking life from them in a quick and careful manner. But we do deny the right of man to inflict torture upon brutes, and thus convert their lives from a blessing into a curse. Such torture has been inflicted upon tens of thousands of animals by vivisection; and no legislation that ingenuity can devise will, we believe, suffice to guard against the repetition of it so long as it is sanctioned in any way as a method of research. The use of vivisection--if it have any use--is practically inseparable from abuse. We therefore call upon our countrymen to forego the poor bribes of possible use which are offered to them, and of which we have now seen a "unique and impressive" example, and generously and manfully to say of vivisection as they once said of slavery "We will have none of it." I am, Sir, yours, etc., FRANCES POWER COBBE. Hengwrt, Dolgelly, Dec. 28, 1884. II. [_Report of American Anti-vivisection Society, Jan. 1888._] "There remain two grounds to adopt: one the total abolition of all experiments; the other the total abolition of all _painful_ experiments. This latter position, which is the one that Dr. Bigelow of Boston and Dr. Leffingwell have assumed, has engaged our attention for a long time; but, after bestowing upon it careful consideration, we feel that we must give it up as impracticable. To secure immunity from pain there must be absolutely perfect anaesthesia. This can be only obtained in two ways: one is by trusting to the experimenter himself to give sufficient of the anaesthetic; the other to insist that an assistant shall be present for the express purpose of keeping the animal under perfect anaesthesia. Now is it anyway likely that either of these conditions would be observed?" III.