These are extreme instances, but they are also in a measure representative of a frightfully general social evil. Is it any wonder if asylums for the insane gape for such men? There comes to them at last a season of business embarrassment; or, when they get to be fifty or thereabouts, the brain begins to feel the strain, and just as they are thinking, "Now we will stop and enjoy ourselves," the brain, which, slave-like, never murmurs until it breaks out into open insurrection, suddenly refuses to work, and the mischief is done. There are therefore two periods of existence especially prone to those troubles,--one when the mind is maturing; another at the turning-point of life, when the brain has attained its fullest power, and has left behind it accomplished the larger part of its best enterprise and most active labor. I am disposed to think that the variety of work done by lawyers, their long summer holiday, their more general cultivation, their usual tastes for literary or other objects out of their business walks, may, to some extent, save them, as well as the fact that they can rarely be subject to the sudden and fearful responsibilities of business men. Moreover, like the doctor, the lawyer gets his weight upon him slowly, and is thirty at least before it can be heavy enough to task him severely. The business man's only limitation is need of money, and few young mercantile men will hesitate to enter trade on their own account if they can command capital. With the doctor, as with the lawyer, a long intellectual education, a slowly-increasing strain, and responsibilities of gradual growth tend, with his out-door life, to save him from the form of disease I have been alluding to. This element of open-air life, I suspect, has a share in protecting men who in many respects lead a most unhealthy existence. The doctor, who is supposed to get a large share of exercise, in reality gets very little after he grows too busy to walk, and has then only the incidental exposure to out-of-door air. When this is associated with a fair share of physical exertion, it is an immense safeguard against the ills of anxiety and too much brain-work. For these reasons I do not doubt that the effects of our great civil war were far more severely felt by the Secretary of War and President Lincoln than by Grant or Sherman.