The number of light photons produced in the scintillation fluid is
proportional to the energy transferred by the incoming gamma rays. For
example, gamma rays emitted by potassium-40 have 1.46 million electron
volts (Mev) energy; those of cesium-137 have 0.660 Mev energy. When both
these radionuclides are producing flashes of light in the scintillation
fluid at once, the photomultiplier tubes produce two different strengths
of electrical pulses. Electronic devices called multichannel
pulse-height analyzers sort and record the number of each.
POTASSIUM-40 IN HUMAN BODIES
Data from whole body counters indicate that potassium-40 is the most
abundant radionuclide in the human body. Our bodies also contain other
naturally radioactive substances but the numbers of atoms usually
present are so low (as with radium for instance) that they cannot be
detected with whole body counters. Several man-made radionuclides also
have found their way into body tissues and organs in quantities that
sometimes are large enough to be detected and counted.
Measurement of disintegrating potassium-40 atoms in the tissues of a
human body can be used to determine the total amount of potassium (both
radioactive and stable) in the body. It is known that potassium-40 makes
up 0.0119% of all potassium and that 11% of all disintegrating
potassium-40 atoms emit high-energy gamma rays that are measurable by
the counter.
The method of determining the amount of potassium in a human subject is
to compare the number of gamma rays from a known amount of potassium
placed in a phantom, or dummy body, with the number counted from the
human subject (see photo on next page). Phantoms are artificial bodies,
approximately the size, shape, and density of a human body, used for
calibrating counters. They are designed so the radioisotopes they
contain have similar distribution to the distribution of the isotopes
expected in the real body. This is how a test might work:
Counts per minute from 140 grams of potassium in the phantom 16,800
Counts per minute with nothing in counter (background) 12,000
Net counts per minute from 140 grams of potassium 4,800
Counts per minute with a 77-pound boy in counter 14,400
Background cunts per minute 12,000
Net count per minute from boy 2,400
Calculated amount of potassium in boy 70 grams
[Illustration: Figure 7 _Phantom used for iodine-131 studies. The
radiation spectrum from the thyroid area in the neck is being obtained
with a sodium iodide crystal, left._]
We can appreciate the sensitivity of whole body counters by comparing
the number of gamma rays recorded by the instruments with the total
number emitted from the body being counted. The following data, also
simplified, illustrate this comparison:
Public-domain text, read in full here on John Shaqi.
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