National events, however, prevented him from pursuing his research work. Having been a member of the responsible body of the Armenian Revolutionary Dashnaktzoutiun (Federation) since 1896, he took part in all the movements which aimed to protect the moral and physical well being of the Armenian people from Turkish and Russian despotism. For example, in 1905, when the Caucasian Tartars, with the approval of the Russian government, began to massacre the Armenians in divers parts of the Caucasus, Dr. Pasdermadjian became a member of the Committee created by the Armenian Revolutionary Dashnaktzoutiun (Federation) to organize defence work among the Armenian people. In November of the same year, when the Armeno-Tartar hostilities began right in Tiflis, under the very nose of the Russian administration, he was entrusted with the command of the Armenian volunteers to protect Tiflis and its environs. During the seven-day struggle which took place in the streets of Tiflis, 500 Armenian volunteers faced nearly 1400 armed Tartars, and drove them back with heavy losses. The situation in the Caucasus was almost normal, and Dr. Pasdermadjian and his idealistic colleagues were about to resume their main object,--to carry arms and ammunition from the Caucasus to the Turkish Armenians in order to prepare them for self-defense,--when the Turkish revolution came in 1908. The Armenians in Erzeroum, as well as the party to which he was a member, telegraphed to Dr. Pasdermadjian and strongly urged him to become their candidate in the coming elections for Representative to the Ottoman Parliament. After seven years of professional studies, Dr. Pasdermadjian had been able to create for himself in the Caucasus a life fairly prosperous financially. He had just secured the right to develop a copper mine, and was about to work it in partnership with a large company. His business required that he should stay in the Caucasus to continue his successful enterprise, but he yielded to the moral pressure of his comrades and left his personal affairs to go to Constantinople as a deputy from Erzeroum.