That spirit, or malady, which penetrated and ruled almost every creature in the eighteenth century found its most notable victim in Marie de Vichy-Chamrond--Mme. du Deffand. She, so to speak, yawned out her life in a blasé society without faith or ideal. That horrible affliction, with all its painful symptoms, ennui, whose origin was seen to lie in an excess and abuse of _esprit_ in a society that based all its pleasures and happiness upon the mind without any higher interest than the self, infected a whole century with an "irremediable disenchantment of others and one's self." This self-cult, or life in and for the mind, developed sagacity, justness of views, and an incomparable penetration, but it neglected all the elements necessary to contentment and those other pleasures, of which the first is love for one's fellow beings. Mme. du Deffand exemplified this stage of mental unbalance; and when she wrote of her former friend and companion: "Mlle. de Lespinasse died to-day at two o'clock; formerly, that would have been an event for me; to-day, it is nothing at all," she gave an idea of the indifference which was characteristic of the society of the time--an indifference which developed into an incurable malady and an all-consuming egoism, stifling the heart-beat of that world which was weary of everything and yet was unwilling to close its eyes. Marie de Vichy-Chamrond was born in 1697, of a noble family. She began the same manner of life as that followed by most French women, being reared in the Convent of Madeleine de Frénel, where, when quite young, she evinced a strong spirit of impiety, giving expression to the most sceptical opinions upon religious subjects, to the great dismay of her superiors and parents. At the age of twenty she was married to the Marquis du Deffand, who had but his brevet of colonel of a regiment of dragoons, and whose intelligence and fortune were of a _nullité rare_. However, her marriage was a sort of emancipation which enabled her to enter society; and it is asserted that she soon became the mistress of Philippe of Orléans, the regent, from whom she received six thousand francs life income.