As the result of a disagreement, she separated from her husband, and then began a life of pleasure among the gayest of the most fashionable world, where, through the power of her brilliancy, wit, charm, and fascinating beauty, she immediately became a leader. After passing through all the phases of social life and its varied experiences--from the society of Mme. de Prie, the type of the dissolute woman of the Regency, from the famous suppers of the regent, whose ingenious inventions of lewd and wanton pleasures made him notorious, from an association with the intriguing Duchesse de Maine, to all the great and influential social centres of Paris--in short, after pursuing a career of fashionable dissipation, she became reconciled to her husband, and lived with him in peace and happiness for a short time; but six months of regular life affected her behavior toward the poor marquis to such a degree that he thought it best to leave her. After that episode, she returned to her lover; and, rejected by him and her friends, and becoming the subject of the gossip of the entire city, she sought consolation from one acquaintance after another, and was miserable all the time. At the age of about thirty-four, Mme. du Deffand returned to a kind of regular life, and, in time, won a reputation for _esprit_, regained her honorable friends and established for herself a kind of accepted authority. Thus, when she opened a salon in 1742, she was able to attract a brilliant company, which became famous after 1749, when she took apartments in the Convent Saint-Joseph. Here wit and polished manners, taste, vivacity, and good sense were the requisites; literature, politics, and philosophy were not tolerated, but "sparkling _bons mots_, glancing epigrams, witty verses, were the avenues to social success."