to you with proper qualifications and limitations on an occasion like this--but there is also a sense in which it is true that every animal body is made up of an aggregation of minute particles of protoplasm, comparable each of them to the individual separate yeast plant. And those who are acquainted with the history of the wonderful revolution which has been worked in our whole conception of these matters in the last thirty years, will bear me out in saying that the first germ of them, to a very great extent, was made to grow and fructify by the study of the yeast plant, which presents us with living matter in almost its simplest condition. Then there is yet one last and most important bearing of this yeast question. There is one direction probably in which the effects of the careful study of the nature of fermentation will yield results more practically valuable to mankind than any other. Let me recall to your minds the fact which I stated at the beginning of this lecture. Suppose that I had here a solution of pure sugar with a little mineral matter in it; and suppose it were possible for me to take upon the point of a needle one single, solitary yeast cell, measuring no more perhaps than the three-thousandth of an inch in diameter--not bigger than one of those little coloured specks of matter in my own blood at this moment, the weight of which it would be difficult to express in the fraction of a grain--and put it into this solution. From that single one, if the solution were kept at a fair temperature in a warm summer's day, there would be generated, in the course of a week, enough torulae to form a scum at the top and to form lees at the bottom, and to change the perfectly tasteless and entirely harmless fluid, syrup, into a solution impregnated with the poisonous gas carbonic acid, impregnated with the poisonous substance alcohol; and that, in virtue of the changes worked upon the sugar by the vital activity of these infinitesimally small plants. Now you see that this is a case of infection. And from the time that the phenomenon of fermentation were first carefully studied, it has constantly been suggested to the minds of thoughtful physicians that there was a something astoundingly similar between this phenomena of the propagation of fermentation by infection and contagion, and the phenomena of the propagation of diseases by infection and contagion. Out of this suggestion has grown that remarkable theory of many diseases which has been called the "germ theory of disease," the idea, in fact, that we owe a great many diseases to particles having a certain life of their own, and which are capable of being transmitted from one living being to another, exactly as the yeast plant is capable of being transmitted from one tumbler of saccharine substance to another. And that is a perfectly tenable hypothesis, one which in the present state of medicine ought to be absolutely exhausted and shown not to be true,