Mr. Greenhow's prescriptions were confined at first to opiates, and other medicines to alleviate symptoms. The opiates were not taken in excess--as, indeed, the books written in the period would conclusively prove. The patient's suffering was so great, however, that extreme recourse to such palliatives might have been forgiven. She could not raise the right leg; and could neither sit up for the faintness which then ensued, nor lie down with ease because of the pain in her back. "She could not sleep at night till she devised a plan of sleeping under a basket, for the purpose of keeping the weight of the bed-clothes from her; and even then she was scared by horrors all night, and reduced by sickness during the day. This sickness increased to such a degree that for two years she was extremely low from want of food." At the end of two years, that is to say, in September, 1841, Sir Charles Clarke, M.D., was called in consultation; and he prescribed iodine, remarking at the same time that, in his view, such a case as hers was practically incurable, and admitting that he "had tried iodine in an infinite number of such cases, and never knew it avail." For the next _three years_ Miss Martineau took three grains per diem of iodide of iron. It relieved the sickness; but up to April, 1844 (two and a half years from the commencement of its administration), Mr. Greenhow did not pretend that any improvement in the physical condition had taken place. In that month, as he afterwards said, he believed he found a slight change, "but he was not sure"; and, if any, it was very trifling. The patient, on her part, was quite convinced that her state then was in no way altered. More than once different friends--amongst them Lord Lytton, Mr. Hallam, and the Basil Montagus--had urged her to try mesmerism; but she had thought it due to her relative to give his orthodox medicines the fullest trial, before taking herself out of his hands in such a way. In June, 1844, however, Mr. Greenhow himself suggested that she should be mesmerized. Of course, so advised, she consented to make the trial. A Mr. Hall, brought by Mr. Greenhow, accordingly mesmerized her for the first time on June 22d, 1844, and again on the following day. The patient thought she experienced some relief, but did not feel quite sure. "On occasion of a perfectly new experience, scepticism and self-distrust are strong."[11] The next day, however, set her doubts at rest. Mr. Hall was unable to come to her, and she asked her maid to make the passes in his stead. [11] This and the succeeding quotations are from her "Letters on Mesmerism," published in the _Athenaeum_, 1845.