Before Marguerite's death, her literary circle had been broken up by the hatred of religious persecutors. Already, in 1536, the imprudent boldness of Marot had rendered it impossible to protect him any longer, and he had been obliged to retire to a place of concealment, from whence he sometimes paid a stealthy visit to her court. His place of _valet-de-chambre_ was given to a man of talents, even more remarkable, and who shared equally the personal esteem of the queen of Navarre, Bonaventure des Periers. Marot's successor paid a graceful compliment to him in a short poem entitled "L'Apologie de Marot absent," published in 1537. The earlier part of the year following witnessed the publication of the most remarkable work of Bonaventure des Periers, the "Cymbalum Mundi," concerning the real character of which writers are still divided in opinion. In it Des Periers introduced a new form of satire, imitated from the dialogues of Lucian. The book consists of four dialogues, written in language which forms a model of French composition, the personages introduced in them intended evidently to represent living characters, whose names are concealed in anagrams and other devices, among whom was Clement Marot. It was the boldest declaration of scepticism which had yet issued from the Epicurean school represented by Rabelais. The author sneers at the Romish church as an imposture, ridicules the Protestants as seekers after the philosopher's stone, and shows disrespect to Christianity itself. Such a book could hardly be published in Paris with impunity, yet it was printed there, secretly, it is said, by a well-known bookseller, Jean Morin, in the Rue St. Jacques, and therefore in the immediate vicinity of the persecuting Sorbonne. Private information had been given of the character of this work, possibly by the printer himself or by one of his men, and on the 6th of March, 1538, when it was on the eve of publication, the whole impression was seized at the printer's, and Morin himself was arrested and thrown into prison. He was treated rigorously, and is understood to have escaped only by disavowing all knowledge of the character of the book, and giving up the name of the author. The first edition of the "Cymbalum Mundi" was burnt, and Bonaventure des Periers, alarmed by the personal dangers in which he was thus involved, retired from the court of the queen of Navarre, and took refuge in the city of Lyons, where liberal opinions at that time found a greater degree of tolerance than elsewhere. There he printed a second edition of the "Cymbalum Mundi," which also was burnt, and copies of either edition are now excessively rare.[98] Bonaventure des Periers felt so much the weight of the persecution in which he had now involved himself, that, in the year 1539, as far as can be ascertained, he put an end to his own existence. This event cast a gloom over the court of the queen of Navarre, from which it seems never to have entirely recovered.