A Mechanical Account of Poisons in Several Essays — John Shaqi
A Mechanical Account of Poisons in Several EssaysMead, Richard
Science
A Mechanical Account of Poisons in Several Essays
Mead, Richard
Poisons -- Early works to 1800; Venom -- Physiological effect -- Early works to 1800
And hence it follows, that whatsoever _Power_ is sufficient to
make a Change in this Attraction, or Cohæsion of the Parts, makes
an Alteration of the Nature of the Fluid; that is, as the Chymists
express it, puts it into a _Fermentation_. And if any one shall think
it necessary to enquire into the particular Manner of producing such
an Effect, we may perhaps in so abstruse a Matter not improbably
Conjecture _thus_, That our Blood consisting chiefly of Two Parts, a
simple _Lymph_, and an infinite Number of small _Globules_, containing
a very subtle and elastic Fluid, these acute Salts, when mingled with
it, do prick those Globules, or _Vesiculæ_, and so let out their
imprisoned active Substance, which expanding it self every way,
must necessarily be the Instrument of this speedy Alteration and
Change (15). From such an _Hypothesis_ as this (and, it may be, not
very easily from any other) we may account for many of the surprizing
Phænomena in the Fermentations of Liquors; and as precarious as
it seems, its Simplicity, and Plainness, and Agreement with the
forementioned Doctrine, will, I believe, recommend it before any other
to those who are not unacquainted with _Geometrical_ Reasonings. But I
wave these Considerations at present, and shall only add One Remark or
Two with Relation to the purpose in Hand, and so proceed.
In the first place then, we may from this _Theory_, learn, how it comes
to pass that so small a Portion of Juice should infect so great a
quantity of Liquor; for in order to do this, it is not necessary that
the Venom should be at the very first mixt with all its Parts; but it
is sufficient that it prick some of the _Bladders_, and the elastic
Matter of these being let out, will be a nimble _Vehicle_ to the acute
Salts, and not only by its activity disperse them thro’ the Fluid,
but restore to them their decreasing _Force_, and thus continue their
Effects, till a great part of the Liquor undergoes at least, in some
Degree, the like Alteration.
And this will the more easily happen in the present Case, because
the _Force_ with which this Poison is thrown into the Blood, as
appears from the Mechanism of the discharging Organs, is very great,
and consequently its Effects will be proportionably violent, or the
Mischief more large and diffused.
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