The phenomena of nature are most often enveloped by so many strange circumstances, and so great a number of disturbing causes mix their influence, that it is very difficult to recognize them. We may arrive at them only by multiplying the observations or the experiences, so that the strange effects finally destroy reciprocally each other, the mean results putting in evidence those phenomena and their divers elements. The more numerous the number of observations and the less they vary among themselves the more their results approach the truth. We fulfil this last condition by the choice of the methods of observations, by the precision of the instruments, and by the care which we take to observe closely; then we determine by the theory of probabilities the most advantageous mean results or those which give the least value of the error. But that is not sufficient; it is further necessary to appreciate the probability that the errors of these results are comprised in the given limits; and without this we have only an imperfect knowledge of the degree of exactitude obtained. Formulæ suitable to these matters are then true improvements of the method of sciences, and it is indeed important to add them to this method. The analysis which they require is the most delicate and the most difficult of the theory of probabilities; it is one of the principal objects of the work which I have published upon this theory, and in which I have arrived at formulæ of this kind which have the remarkable advantage of being independent of the law of the probability of errors and of including only the quantities given by the observations themselves and their expressions.