It appears, therefore, that, even under the very imperfect practice of Vaccination which has taken place in this metropolis, 23,134 lives have been saved in the last fifteen years, according to the best computation that the _data_ afford. It will be seen, by an inspection of the Table, that in that time there have been great fluctuations in the number of deaths. This has been owing partly to the Small Pox Inoculation of out-patients having, by an unaccountable infatuation, been kept up at the Small Pox Hospital for several years after the virtue of Vaccination had been fully confirmed. The greater number of deaths in 1805 may chiefly be referred to this cause. Since the suppression of this practice, the adoption of Vaccination, though in a degree so incomplete, in consequence of public prejudice, created entirely by mischievous publications, has been unable to prevent a considerable, though fluctuating, mortality from Small Pox. The late mortality from Small Pox, though little more than one half of what it was in former times, might have been entirely saved, if Vaccination had been carried to the same extent as in many cities and whole districts on the continent of Europe, in Peru, and Ceylon. In the summer of 1811 the author was called to visit, professionally, Don Francisco de Salazar, who had arrived a few days before in London, on his route from Lima to Cadiz, as a deputy to the Spanish Cortes. He informed him, that Vaccination had been practised with so much energy and success in Lima, that for the last twelve months there had occurred, not only no death from, but no case of, Small Pox; that the new-born children of all ranks are carried as regularly to the Vaccinating House as to the font of baptism; that the Small Pox is entirely extinguished all over Peru; nearly so in Chili; and that there has been no compulsory interference on the part of the government to promote Vaccination.