THOMAS CONOLLY, æt. 58, labourer. Admitted on 7th day of fever: severe pain of head early in the attack which has continued without intermission, accompanied with vertigo; scarcely any sleep; face flushed; no uneasiness of chest; abdomen not tender; no stool for four days; tongue loaded and dry; pulse 96, weak. 8th. Less pain of head; no improvement in other symptoms; pulse 92. 9th. Scarcely any pain of head; no sleep; delirium; muscular tremor; tongue brown and dry; pulse 111. 10th. Pain quite gone; more insensible; constant talkative delirium; colour of cheek dusky, almost livid; respiration hurried; stools and urine in bed; pulse 112, feeble. 11th. Died. _Head._ Membranes vascular; arachnoid thickened and opake; substance of brain highly vascular and preternaturally firm; some fluid beneath membranes and in ventricles. _Thorax._ [Pleuræ adherent;] lungs gorged with blood. _Abdomen._ Liver and spleen exceedingly softened, readily breaking down beneath the finger. CASE XLI. MARY TIFFIN, æt. 25, servant. Perfectly insensible: no account can be obtained of history or duration of disease: abdomen tender; tongue loaded, moist; pulse 99. 2d day after admission scarcely any sleep; delirium; muscular tremor. 3d. Insensibility continues; constant delirium; has passed neither stool nor urine; latter drawn off by catheter; pulse 124, feeble and fluttering. Died next morning. _Head._ Dura mater and arachnoid natural; pia mater vascular; substance of brain highly vascular and unusually firm; cerebellum soft; effusion beneath arachnoid and at base. _Thorax._ [Substance of both lungs filled with miliary tubercles.] _Abdomen._ [Liver studded with tubercles, similar to those of the lungs; spleen full of the same kind of tubercles, excepting that they were larger, and some of them were suppurating;] pancreas extremely firm. CASE XLII. MARY POULSTON, æt. 50. No account to be obtained of duration of disease: lies quite insensible and prostrate; frequent jactitation of the arms; face flushed; respiration stertorous; cheeks alternately expanding and collapsing during inspiration and expiration; tongue not to be protruded; stools and urine in bed; pulse 138, weak, and easily compressed. 2d. Died. _Head._ Dura mater vascular; arachnoid thickened and opake; substance of brain highly vascular and firm. _Thorax._ All the viscera perfectly healthy. _Abdomen._ Mucous membrane of intestines vascular, without ulceration; mesentery inflamed; [contained a calcareous deposit of an oval shape included in a cyst.] CASE XLIII. WILLIAM ASHLEY, æt. 65, messenger. Admitted on 4th day of fever: slight occasional head-ache; mind distinct; scarcely any sleep; face flushed; no uneasiness of chest or abdomen; slight cough; pulse 81. 5th. Slight head-ache; little sleep; pulse 82. 6th. Pain of head gone; pulse 90.