8th. No pain; mind confused; delirium; stools in bed; pulse 108. 10th. Prostration; pulse 111. 11th. Perfectly insensible; great prostration; deglutition difficult; hiccup; pulse 116, extremely feeble. 12th. Died. _Head._ Membranes and substances of brain intensely vascular; perhaps as much so as in pure phrenitis; substance exceedingly firm; viscera of thorax and abdomen healthy. CASE XLIV. FRANCIS HODGKINSON, æt. 15, servant. Admitted on the 8th day of fever: pain of head and vertigo, which ushered in the attack already gone; mind confused; scarcely any sleep; slight pain of chest on full inspiration; slight cough; abdomen not tender; tongue red at margin, centre covered with yellow fur; pulse 117, easily compressed. 9th. No pain; much confusion; much restlessness; respiration oppressed; tongue still moist; lips and teeth sordid; stools in bed; pulse 112. 13th. Petechiæ; tongue dry; pulse 110. 15th. No material change in symptoms. Died. _Head._ Membranes vascular; substance exceedingly vascular and firm; some fluid in ventricles and at base. _Thorax._ Lower lobe of left lung of dark red colour and inflamed. _Abdomen._ Mucous membrane of small intestines vascular, and of dark red colour. CASE XLV. WILLIAM WHITE, æt. 17, labourer. Admitted on 6th day of fever: pain of head; especially over forehead; mind distinct; some sleep; face flushed; no thoracic or abdominal uneasiness; tongue white and dry; no stool for a week; pulse 126. 7th. Pain of head very severe; pulse 117; V. S. ad ℥xij. 8th. Died this morning most suddenly and unexpectedly, after having complained of violent pain of the head. _Head_, not examined till three days after death, yet the substance of the brain was exceedingly firm, and seemed to distend and protrude its membranes, so that there seemed something like hypertrophy of its substance; viscera of thorax and abdomen healthy. CASE XLVI. JOHN MULLINS, æt. 28, servant. Stated to be a relapse after a fever of three weeks duration: at present, lies perfectly senseless; noisy delirium; extreme restlessness; pulse 70. 2nd day after admission, continues perfectly insensible; respiration slow and stertorous; tongue not to be protruded; stools passed in bed; pulse 60. 6th. Remained nearly in the same state until this morning. Died.