But the definiteness and the consistency with which the nuclear division stages occur in any given species of ameba, lends support to the probability that in these animals the relation existing between the chromatin and the cytoplasm are similar to those observed in higher animals; and that the laws governing the transmission of cytoplasmic characters in amebas are quite as inflexible as those governing somatoplasmic characters in the higher organisms. Among the investigators of cytologic and genetic phenomena (among the multicellulars) the belief is practically unanimous that the elaborate mechanism involved in nuclear division is primarily a design for distributing the factors concerned in heredity. Now it would be very strange indeed if a similar and quite as complicated a mechanism in ameba had no function to perform. For what would be the purpose of the complicated nuclear changes in ameba if not concerned with heredity? As has already been seen, however, there are numerous cytoplasmic characters, in the larger amebas at least, that are inherited from one generation to the next with as little variation as is observed in other organisms (Schaeffer, ’16). The recent work of Jennings (’16) on _Difflugia_ and Hegner (’18) on _Arcella_ also indicates that the general processes of inheritance in these organisms which are closely related to amebas, are similar to those observed in higher forms. The conclusion seems justified therefore that the nuclear changes in amebas mean essentially the same thing as in other organisms. We are now therefore in a position to say that amebas are definitely and thoroughly organized; that they are not really “shapeless”; that they are not more subject to variation than a higher organism is; and that each species differs from all others in probably every visible detail. The large variety of pseudopods observed in different species are seen not to be the result of physical or extrinsic chemical forces acting upon ectoplasms differing in some mere physical character as viscosity. But all these peculiarities are hereditary, and are due to a fundamental chemical structure of the protoplasm which is specific for the species. The highly characteristic nature of the pseudopods formed by the amebas of any species, it is seen, is to be referred to the fundamental structure of the protoplasm, probably its stereochemical structure. And what is of especial importance for this discussion, the character of streaming concerned with pseudopod formation and with movement in general, which is specific for each species, is likewise found, to some extent at least, to be conditioned by the specific structure of the protoplasm.