Written at various times during a period extending over several years, a critic will undoubtedly discover instances of repetition and re-statement. Now and then, it has seemed advisable to include matter from earlier writings, long out of print; and new light has been thrown upon some phases of a perplexing problem. Will it tend to induce conviction of the need for reform? Assuredly, this is not to be expected where there is disagreement regarding certain basic principles. First of all, there must be some common ground. No agreement regarding vivisection can be anticipated or desired with any man who holds that some vague and uncertain addition to the sum total of knowledge would justify experiments made upon dying children in a hospital, without regard to their personal benefit, or sanction the infliction of any degree of agony upon animals in a laboratory. A liking for the use of italics as a means of directing attention to certain statements is confessed. But wherever such italicized phrases appear in quotations, the reader should ascribe the emphasis to the writer, and not to the original authority. The inculcation of scepticism regarding much that is put forth in justification of unlimited research is admitted. It seems to the writer that anyone who has become interested in the question would more wisely approach it with a tendency toward doubt than toward implicit belief; to doubt, however, that leads one directly to investigation. We need to remember, however, that inaccuracy by no means connotes inveracity. There is here no imputation against the honesty of any writer, even when carelessness, exaggeration and inaccuracy are not only alleged, but demonstrated to exist. A. L. Aurora, N.Y., 1914 --------- PREFACE TO THE SECOND EDITION Another edition of this work being called for, the opportunity for one or two emendations is afforded. In the first chapter of the present work, reference is made to the antivivisection societies of England, and, relying upon evidence given before the Royal Commission in 1906, one of them is mentioned as the "principal organization." The relative standing or strength of the different societies at the present time would appear not to be determined or easily determinable, and, of course, what was fact in 1906 may not be at all true ten years later. The matter would seem to be of little importance as compared with the greater questions pertaining to reform; but in the interest of accuracy the author would now prefer to make no pronouncement concerning the relative rank of the English societies, leaving decision as to precedence to those who give them financial support.