Sometimes in typhus, the affection of the spleen shows itself again, even after recovery has fairly set in; the intermittent type again breaks forth, and recovery finally takes place, as the intermissions become more and more distinct and lengthened. As long as the intermittent type continues, Apis has to be given; the action of the spleen becomes more and more normal, the fever paroxysms become shorter and less marked, and the restoration of health is effected without any more treatment than a single dose of Apis 30, one globule, which is permitted to act until the patient is well. Observations of this kind, which I have made under the most diversified circumstances, have taught me that Apis is _the most sovereign remedy for all those morbid processes which we designate as_ INTERMITTENT FEVER. The following symptoms indicate the homœopathicity of Apis to intermittent fever: "1081: every afternoon about three or four o'clock she feels chilly, shivering, worse in warmth; a chilly creeping along the back, the hands seem dead; in about an hour she feels feverish and hot, with rough cough, hot hands and cheeks, without thirst; these symptoms pass off gradually, after which she feels heavy and prostrate. 1088: chilliness all over, recurring periodically, with an undulating sensation. 1089: chill after a heat of thirty-six hours. 1090: sudden chilliness, followed by heat and sweat. 499: loathing, with chilliness and coldness of the limbs. 534: pains on the left side, below the last ribs. 535: violent burning pain below the short ribs, on both sides, worst and most permanent on the left side, where it continues for weeks, preventing sleep. 577: enlargement of the abdomen, with swelling of the feet, scanty urine." The provings of Apis show that this drug affects every portion of the nervous system--the cerebral, spinal and ganglionic nerves--and the process of sanguification, in the same general and characteristic manner as is the case in fever and ague. In comparing the symptoms of Apis with those of any other known drug, there is no medicine that bears as close an affinity to fever and ague as Apis. Howsoever useful other remedies may have proved, in the treatment of fever and ague, they are only homœopathic to isolated conditions, in comparison with Apis. In practice, it was often found very difficult, even for the most experienced physician, to decide in which of these exceptional cases the specifically homœopathic agent should have been employed. Sometimes no properly homœopathic remedy could be found, in which case the treatment had to be conducted in a round-about way.